Functional Status of the Cardiovascular System and Metabolic Disorders Among Indigenous Population of Republic of Sakha (Yakutia)

According to the results of analytical, observational cross-sectional research on a random sample of the indigenous population of the Republic of Sakha (Yakutia) the association between the level of cardiovascular function and metabolic parameters was studied. It was found that 14 % of the participants bore the marks of "poor adaptation", 10 % - "failure of adjustment mechanisms." In senior age groups, the number of persons with dysaptation signs increased to 48 %. We found that the failure of adjustment mechanisms was manifested itself as negative changes in the metabolic profile and as increase of frequency of metabolic disorders and their combinations. Functional changes index based on the indicators of circulatory system, age, height and body mass shows good indices of sensitivity and specificity, and allows identifying 83 % of persons with multiple metabolic disorders correctly. The facts suggest the possibility of screening technology optimization in identifying risk factors of inveterate non-communicable diseases in limited health care resources. A holistic approach to the human body as a universal biosystem, knowledge deepening of its parameters under various external influences can help to optimize the methods of distress prevention

Biology · Body mass index · Distress · Environmental health · Indigenous · Metabolic syndrome · Obesity · Pathology · Population · Clinical Psychology · Healthcare Systems and Public Health · Human Health and Disease · Medicine · Nutrition, Genetics, and Disease · Gerontology

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