Valentina I Fedorova
Biographic Data
| ID | 4324237 |
|---|---|
| NAME | Valentina I Fedorova |
| GIVEN NAMES | Valentina I |
| FAMILY NAME | Fedorova |
| SIGNATURE | FEDOROVA V I |
| AFFILIATIONS | North-Eastern Federal University |
| ORCID | 0000-0002-6147-4643 |
| VERIFIED | Yes |
| TOTAL WORKS | 11 |
| TOTAL CITATIONS | 9 |
| AUTHOR COUNT | 11 |
| EDITOR COUNT | 0 |
| FIRST PUBLICATION YEAR | 2011 |
| LATEST PUBLICATION YEAR | 2022 |
| H-INDEX | 1 |
Brown adipose tissue thermogenesis among young adults in northeastern Siberia and Midwest United States and its relationship with other biological adaptations to cold climates
OBJECTIVES: Recent research suggests that brown adipose tissue (BAT) plays a functional role in non-shivering thermogenesis; however, few studies have examined population variation in BAT or its relationship with other mechanisms of adaptation to cold stress. This study characterized BAT thermogenesis and other adaptive responses to low temperatures among Indigenous Siberian young adults and young adults living near Chicago, IL. MATERIALS AND MET…
Evidence for a sensitive period of plasticity in brown adipose tissue during early childhood among indigenous Siberians
OBJECTIVES: Evolutionary theorists have debated the adaptive significance of developmental plasticity in organisms with long lifespans such as humans. This debate in part stems from uncertainty regarding the timing of sensitive periods. Does sensitivity to environmental signals fluctuate across development or does it steadily decline? We investigated developmental plasticity in brown adipose tissue (BAT) among indigenous Siberians in order to exp…
Brown adipose tissue, energy expenditure, and biomarkers of cardio‐metabolic health among the Yakut (Sakha) of northeastern Siberia
OBJECTIVES: This study provides the first investigation of non-shivering thermogenesis (NST) and brown adipose tissue (BAT) activity among an indigenous circumpolar population, the Yakut of northeastern Siberia. The study also examines the health significance of BAT activity in this population by testing the relationships between BAT thermogenesis and biomarkers of cardio-metabolic disease risk, such as percent body fat and blood glucose and chol…
Lifestyle mediates seasonal changes in metabolic health among the yakut (sakha) of northeastern siberia
OBJECTIVES: Among indigenous circumpolar populations, extreme seasonality influences food availability and energy metabolism. Furthermore, subsistence patterns and wage labor opportunities shift with season. Thus, health measures among circumpolar populations likely exhibit seasonal changes that are influenced by lifestyle factors. This study examines how markers of cardio-metabolic health vary between summer and winter as a function of an indivi…
Adiponectin, hemoglobin, and cardiovascular risk in an indigenous siberian population
OBJECTIVES: Adipose tissue hypoxia appears to play a role in promoting chronic inflammation and the development of obesity-related cardiovascular and metabolic diseases, yet the underlying mechanisms are not well understood. The aim of the present research is to examine whether adiponectin levels (an adipocyte-derived hormone with anti-inflammatory properties) are inversely correlated with hemoglobin levels in an indigenous Siberian population. M…
Functional Status of the Cardiovascular System and Metabolic Disorders Among Indigenous Population of Republic of Sakha (Yakutia)
According to the results of analytical, observational cross-sectional research on a random sample of the indigenous population of the Republic of Sakha (Yakutia) the association between the level of cardiovascular function and metabolic parameters was studied. It was found that 14 % of the participants bore the marks of "poor adaptation", 10 % - "failure of adjustment mechanisms." In senior age groups, the number of persons with dysaptation signs…
Socio‐demographic predictors of sleep complaints in indigenous S iberians with a mixed economy
OBJECTIVES: Socio-demographic indicators closely relate to sleep in industrialized populations. However we know very little about how such factors impact sleep in populations undergoing industrialization. Within populations transitioning to the global economy, the preliminary evidence has found an inconsistent relationship between socio-demographics and sleep complaints across countries and social strata. MATERIALS AND METHODS: Surveys were condu…
Seasonal variation in basal metabolic rates among the yakut (Sakha) of Northeastern Siberia
Among the Yakut, increased wintertime BMR was observed among younger but not older adults, whereas all adults showed sharp reductions in free thyroid hormone levels during the winter. Among men, greater participation in subsistence activities was associated with increased BMRs and greater fat oxidation. Among women, variation in food use had the strongest impact on metabolic function
Cholesterol and Risk of Atherosclerosis in Rural Indigenous Population of Republic of Sakha (Yakutia)
According to the results of the cross-sectional study of rural indigenous population of the Republic of Sakha (Yakutia), there has been studied the level of cholesterol and frequency of atherogenic changes of the lipid profile of the blood plasma. It has been found that in 35 % of the surveyed indigenous people, the level of cholesterol was 5.2 mmol/l or more, and in 10.8 % - 6.2 mmol/l or more. Among the persons with high cholesterol, atherogeni…
Seasonal and socioeconomic influences on thyroid function among the Yakut (Sakha) of Eastern Siberia
OBJECTIVES: Previous research has shown that the extreme cold and short day lengths of polar winters promote increased production and uptake of thyroid hormones, resulting in marked declines in free triiodothyronine (fT3). However, this "polar T3 syndrome" has been documented almost exclusively on small samples of male sojourners and little is known about seasonal changes in thyroid function among indigenous circumpolar groups. The present study …
Circumpolar adaptation, social change, and the development of autoimmune thyroid disorders among the Yakut (Sakha) of Siberia
OBJECTIVES: Alterations in thyroid function appear to play a central role in adaptation to Arctic environments. Increased thyroid activity in indigenous circumpolar populations is associated with upregulated metabolism, including elevated basal metabolic rate (BMR); however, little is known about the possible health consequences of these climate-induced changes on thyroid function. The focus of the present study is to determine the prevalence of …
Evidence for a sensitive period of plasticity in brown adipose tissue during early childhood among indigenous Siberians
OBJECTIVES: Evolutionary theorists have debated the adaptive significance of developmental plasticity in organisms with long lifespans such as humans. This debate in part stems from uncertainty regarding the timing of sensitive periods. Does sensitivity to environmental signals fluctuate across development or does it steadily decline? We investigated developmental plasticity in brown adipose tissue (BAT) among indigenous Siberians in order to exp…
Circumpolar adaptation, social change, and the development of autoimmune thyroid disorders among the Yakut (Sakha) of Siberia
OBJECTIVES: Alterations in thyroid function appear to play a central role in adaptation to Arctic environments. Increased thyroid activity in indigenous circumpolar populations is associated with upregulated metabolism, including elevated basal metabolic rate (BMR); however, little is known about the possible health consequences of these climate-induced changes on thyroid function. The focus of the present study is to determine the prevalence of …
Seasonal and socioeconomic influences on thyroid function among the Yakut (Sakha) of Eastern Siberia
OBJECTIVES: Previous research has shown that the extreme cold and short day lengths of polar winters promote increased production and uptake of thyroid hormones, resulting in marked declines in free triiodothyronine (fT3). However, this "polar T3 syndrome" has been documented almost exclusively on small samples of male sojourners and little is known about seasonal changes in thyroid function among indigenous circumpolar groups. The present study …
Seasonal variation in basal metabolic rates among the yakut (Sakha) of Northeastern Siberia
Among the Yakut, increased wintertime BMR was observed among younger but not older adults, whereas all adults showed sharp reductions in free thyroid hormone levels during the winter. Among men, greater participation in subsistence activities was associated with increased BMRs and greater fat oxidation. Among women, variation in food use had the strongest impact on metabolic function
Cholesterol and Risk of Atherosclerosis in Rural Indigenous Population of Republic of Sakha (Yakutia)
According to the results of the cross-sectional study of rural indigenous population of the Republic of Sakha (Yakutia), there has been studied the level of cholesterol and frequency of atherogenic changes of the lipid profile of the blood plasma. It has been found that in 35 % of the surveyed indigenous people, the level of cholesterol was 5.2 mmol/l or more, and in 10.8 % - 6.2 mmol/l or more. Among the persons with high cholesterol, atherogeni…
Socio‐demographic predictors of sleep complaints in indigenous S iberians with a mixed economy
OBJECTIVES: Socio-demographic indicators closely relate to sleep in industrialized populations. However we know very little about how such factors impact sleep in populations undergoing industrialization. Within populations transitioning to the global economy, the preliminary evidence has found an inconsistent relationship between socio-demographics and sleep complaints across countries and social strata. MATERIALS AND METHODS: Surveys were condu…
Lifestyle mediates seasonal changes in metabolic health among the yakut (sakha) of northeastern siberia
OBJECTIVES: Among indigenous circumpolar populations, extreme seasonality influences food availability and energy metabolism. Furthermore, subsistence patterns and wage labor opportunities shift with season. Thus, health measures among circumpolar populations likely exhibit seasonal changes that are influenced by lifestyle factors. This study examines how markers of cardio-metabolic health vary between summer and winter as a function of an indivi…
Adiponectin, hemoglobin, and cardiovascular risk in an indigenous siberian population
OBJECTIVES: Adipose tissue hypoxia appears to play a role in promoting chronic inflammation and the development of obesity-related cardiovascular and metabolic diseases, yet the underlying mechanisms are not well understood. The aim of the present research is to examine whether adiponectin levels (an adipocyte-derived hormone with anti-inflammatory properties) are inversely correlated with hemoglobin levels in an indigenous Siberian population. M…
Functional Status of the Cardiovascular System and Metabolic Disorders Among Indigenous Population of Republic of Sakha (Yakutia)
According to the results of analytical, observational cross-sectional research on a random sample of the indigenous population of the Republic of Sakha (Yakutia) the association between the level of cardiovascular function and metabolic parameters was studied. It was found that 14 % of the participants bore the marks of "poor adaptation", 10 % - "failure of adjustment mechanisms." In senior age groups, the number of persons with dysaptation signs…
Brown adipose tissue, energy expenditure, and biomarkers of cardio‐metabolic health among the Yakut (Sakha) of northeastern Siberia
OBJECTIVES: This study provides the first investigation of non-shivering thermogenesis (NST) and brown adipose tissue (BAT) activity among an indigenous circumpolar population, the Yakut of northeastern Siberia. The study also examines the health significance of BAT activity in this population by testing the relationships between BAT thermogenesis and biomarkers of cardio-metabolic disease risk, such as percent body fat and blood glucose and chol…
Evidence for a sensitive period of plasticity in brown adipose tissue during early childhood among indigenous Siberians
OBJECTIVES: Evolutionary theorists have debated the adaptive significance of developmental plasticity in organisms with long lifespans such as humans. This debate in part stems from uncertainty regarding the timing of sensitive periods. Does sensitivity to environmental signals fluctuate across development or does it steadily decline? We investigated developmental plasticity in brown adipose tissue (BAT) among indigenous Siberians in order to exp…
Brown adipose tissue thermogenesis among young adults in northeastern Siberia and Midwest United States and its relationship with other biological adaptations to cold climates
OBJECTIVES: Recent research suggests that brown adipose tissue (BAT) plays a functional role in non-shivering thermogenesis; however, few studies have examined population variation in BAT or its relationship with other mechanisms of adaptation to cold stress. This study characterized BAT thermogenesis and other adaptive responses to low temperatures among Indigenous Siberian young adults and young adults living near Chicago, IL. MATERIALS AND MET…
Medicine (10 works) · Endocrinology (9 works) · Internal Medicine (8 works) · Anthropometry (6 works) · Biology (6 works) · Demography (5 works) · Physiology (5 works) · Population (5 works) · Adipose tissue (4 works) · Environmental health (4 works)