Genetic Admixture Analysis in the Population of Tacuarembó-Uruguay Using Alu Insertions

Bibliographic Data

ID6068362
AuthorsYasser Vega-Requena, Yasser V Vega-Requena (Universidad de la República de Uruguay), Pedro C Hidalgo (0000-0001-5207-9660, Universidad de la República de Uruguay), Pedro Hidalgo, Elizabeth Ackermann (0000-0002-3714-2550, Universidad de la República de Uruguay), Sara Flores-Gutiérrez (0000-0002-5895-8129, Universidad de la República de Uruguay), Mónica Sans (0000-0002-1564-8761, Universidad de la República de Uruguay)
Year2020
Publication date2020-06-01
Peer ReviewedYes
Open AccessNo
TypeARTICLE
VenueHuman Biology (JOURNAL)
Journal identifiersISSN: 0018-7143 • E-ISSN: 1534-6617
PublisherProject MUSE (PUBLISHER • US)
DOI10.1353/hub.2017.0081
OpenAlexW4297147715
LanguageEN
References cited8

Tacuarembó is a department located in northeastern Uruguay, whose population is the result of several migration waves from Europe and Near East, as well as Africans and Afro-descents mostly from Brazil; these waves settled with the territory’s various Native ethnic groups (Charrúa, Minuán, and Guaraní). In the past, this population has been the focus of genetic studies showing this trihybrid origin, with greater contributions of Natives and Africans than in other Uruguayan regions. In this study we analyzed eight Alu insertions (A25, ACE, APOA1, B65, D1, F13B, PV92, TPA25) to provide valuable information for ancestrality and genetic diffferentiation and to compare with both previous studies on the Tacuarembó population and Alu frequencies in other Uruguayan populations. The European contribution to Alu and classical markers was almost equal to that of a previous study using 22 classical markers (63% vs. 65%), while African contribution was higher (30% vs. 15%), and Native American contribution shows an important diffference in Alu: 7% versus 20%. We found no signifijicant diffferences in genetic diffferentiation between Tacuarembó and Montevideo but signifijicant diffferences between Tacuarembó and Basque descendants from Trinidad. Our results support previous fijindings obtained with classical markers that demonstrate the trihybrid composition of the Tacuarembó population, correlated with historical records. Thus, Alu insertions provide interesting information in light of the admixture process in the Uruguayan population

Alu element · Biology · Ethnic group · Gene · Geography · Population · Sociology · Anthropology · Demography · Forensic and Genetic Research · Genetics

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