Two distinct genotypes (MY-x and MX) of JC virus previously identified in Hokkaido Ainu

Bibliographic Data

ID6135702
AuthorsHuai-Ying Zheng (The University of Tokyo), Hiroshi Ikegaya (0000-0002-2380-7558, The University of Tokyo), Makoto Nakajima (0000-0003-3547-1307, The University of Tokyo), Koichi Sakurada (0000-0003-2115-0262, National Research Institute of Police Science), Tomokazu Takasaka (The University of Tokyo), Tadaichi Kitamura (0000-0002-3009-2546, The University of Tokyo), Yoshiaki Yogo (The University of Tokyo)
Year2005
Volume113
Issue2
Pages225-231
Publication date2005-01-01
Peer ReviewedYes
Open AccessYes
TypeARTICLE
VenueAnthropological Science (JOURNAL)
Journal identifiersISSN: 0918-7960 • E-ISSN: 1348-8570
PublisherAnthropological Society of Nippon (PUBLISHER • JP)
DOI10.1537/ase.040716
OpenAlexW1980995824
LanguageEN
Citations received3
References cited35

Genotyping the urinary JC virus (JCV) DNA is a useful means to gain new insights into the origin of ethnic groups. We recently detected thirteen JCV isolates from the Ainu, an indigenous population living on Japan’s northernmost island (Hokkaido). Based on phylogenetic analysis, these isolates were classified into five genotypes: two (MX and MY-x) were first identified in the Ainu, two (EU-a/Arc and EU-c) are prevalent in northeastern Siberians and an Arctic tribe, and one (MY-b) is widespread among Hondo Japanese, i.e. contemporary Japanese excluding the Ainu. Although these findings have several potential implications for the development of the modern Ainu, further studies are required to reach a definite conclusion. In this report, an isolate in a forensic subject whose ethnic origin was Ainu belonged to the MX genotype and two isolates recently identified in South Koreans and grouped as Native American isolates belonged to the MY-x genotype. The present findings suggest that the MX genotype of JCV is unique to the Ainu, whereas MY-x is spread among some Northeast Asian populations

Biology · Ethnic group · Ethnology · Gene · Genotype · Genotyping · Geography · Indigenous · JC virus · Phylogenetic tree · Population · Progressive multifocal leukoencephalopathy · Sociology · Tribe · Virus · Anthropology · Demography · Full-Duplex Wireless Communications · History · Parvovirus B19 Infection Studies · Polyomavirus and related diseases · Ecology · Genetics · Virology

Tools

Open DOIOpen Access