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Meta-epidemiology and the MetaBLIND study

Response to Tack

Datos Bibliográficos

ID7464802
AutoresHelene Moustgaard (0000-0002-7057-5251, University of Southern Denmark, autor de correspondencia), Asbjørn Hróbjartsson (0000-0002-2451-5012, University of Southern Denmark)
Año2023
Volumen28
Número9
Páginas882-886
Fecha de publicación2023-04-10
Peer ReviewedSí
Open AccessSí
TipoARTICLE
RevistaJournal of Health Psychology (JOURNAL)
Identificadores de la revistaISSN: 1359-1053 • E-ISSN: 1461-7277
EditorialSAGE Publishing (PUBLISHER • US)
DOI10.1177/13591053231167279
PMID37038625
OpenAlexW4364353839
IdiomaEN
Referencias citadas9

In 2020 we published MetaBLIND, a large meta-epidemiological study on the impact of masking on effect estimates in randomized clinical trials (RCTs). While masking is an established methodological practice in RCTs it is not clear to what extent results of non-masked RCTs are biased. Surprisingly, we found no evidence of an impact of masking on effect estimates, on average. Michiel Tack commented on the MetaBLIND study, and here we respond. The issues he raised were examples of standard themes when interpreting meta-epidemiological studies, which we have discussed at some length elsewhere, and did not warrant change of our conclusion. We maintain that the MetaBLIND results do not provide a sufficient basis for recommending abandoning masking as a methodological safeguard

Masking (illustration · Meta-analysis · Pathology · Randomized controlled trial · Warrant · Health Systems, Economic Evaluations, Quality of Life · Medicine · Meta-analysis and systematic reviews · Psychology · Statistical Methods in Clinical Trials · Clinical Psychology · Epidemiology · Surgery

  • Problems with the MetaBLIND study

    Open Access•Michiel Tack•Journal of Health Psychology•2023

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