Brief communication
Multiplex X/Y‐PCR improves sex identification in aDNA analysis
Bibliographic Data
| ID | 8313801 |
|---|---|
| Authors | Diane Schmidt (0000-0001-6606-4398, Institute of Zoology, corresponding author), Hummel (0000-0002-3647-8968, Institute of Zoology), Susanne Hummel, Bernd Herrmann (Institute of Zoology) |
| Year | 2003 |
| Volume | 121 |
| Issue | 4 |
| Pages | 337-341 |
| Publication date | 2003-08-01 |
| Peer Reviewed | Yes |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | American Journal of Physical Anthropology (JOURNAL) |
| Journal identifiers | ISSN: 0002-9483 • E-ISSN: 1096-8644 |
| Publisher | Wiley (PUBLISHER • GB) |
| DOI | 10.1002/ajpa.10172 |
| PMID | 12884315 |
| OpenAlex | W2017278739 |
| Language | EN |
| Citations received | 4 |
| References cited | 28 |
This study introduces a polymerase chain reaction (PCR)‐based multiplex approach to improve the certainty of molecular sex identification on archaeological skeletal material. We coamplified amelogenin, two X‐chromosomal short tandem repeats (STRs) (DXS6789 and DXS9898), and two Y‐specific STRs (DYS391 and DYS392). The amplification results of this multiplex approach back each other up, and enable a reliable sex identification. This coamplification of X‐ and Y‐specific markers in a multiplex assay combines the added advantage of positive identification of both female and male individuals with raising the validity of the diagnosis by obtaining multiple data simultaneously. This multiplex system was successfully applied to 3,000‐year‐old bone material. Am J Phys Anthropol 121:000–000, 2003. © 2003 Wiley‐Liss, Inc
Amelogenin · Biology · Computational biology · Gene · Identification (biology) · Microsatellite · Multiplex · Multiplex polymerase chain reaction · Polymerase chain reaction · Forensic and Genetic Research · Forensic Anthropology and Bioarchaeology Studies · Genetics · Molecular Biology · Molecular Biology Techniques and Applications
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| Unique citing works | 4 |
|---|---|
| Citations per year | 0,22 |
| Citation span | 2008 - 2018 (11) |
| Citation velocity | historical |
| Highly cited | No |
| Citation types | Neutral: 4 |