Multiple fetal and adult hemoglobins in Malaysian Macaca nemestrina
Consequences of a ‐chain variation
Bibliographic Data
| ID | 8316268 |
|---|---|
| Authors | Peter E Nute (National and Kapodistrian University of Athens), H A Pataryas (National and Kapodistrian University of Athens) |
| Year | 1974 |
| Volume | 40 |
| Issue | 1 |
| Pages | 17-25 |
| Publication date | 1974-01-01 |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | American Journal of Physical Anthropology (JOURNAL) |
| Journal identifiers | ISSN: 0002-9483 • E-ISSN: 1096-8644 |
| Publisher | Wiley (PUBLISHER • GB) |
| DOI | 10.1002/ajpa.1330400103 |
| PMID | 4206325 |
| OpenAlex | W2047098768 |
| Language | EN |
| Citations received | 1 |
| References cited | 20 |
The hemoglobins of fetal and adult Macaca nemestrina were investigated electrophoretically and chromatographically. Standard electrophoretic techniques failed to reveal variation in either fetal or adult hemoglobins beyond that previously attributed to the presence of the duplicate γ‐chain loci characteristic of this species. However, column chromatography of whole hemolysates on CM‐Sephadex or of globin chains on CM‐cellulose in 8 M urea revealed that some fetuses had four major hemoglobins and some adults had two major hemoglobin components. All animals examined were of Malaysian origin; the variation described is a consequence of variation in α‐chain structure in Malaysian populations of this species, and of the interaction of different α chains with the products of the duplicate γ‐chain loci
Biology · Fetal hemoglobin · Fetus · Globin · Hemoglobin · Macaca nemestrina · Pregnancy · Sephadex · Biochemistry · Blood groups and transfusion · Genetics · Hemoglobinopathies and Related Disorders · Iron Metabolism and Disorders
| Citations per year | 0.02 |
|---|---|
| Citation span | 1974 - 1974 (1) |
| Highly cited | No |