Hemoglobin variations on a small bahamian island

Bibliographic Data

ID8316742
AuthorsRobert A Halberstein (University of Miami), John E Davies (0000-0002-8733-0082, University of Miami), A K Mack (University of Miami)
Year1981
Volume55
Issue2
Pages217-221
Publication date1981-06-01
Peer ReviewedYes
Open AccessYes
TypeARTICLE
VenueAmerican Journal of Physical Anthropology (JOURNAL)
Journal identifiersISSN: 0002-9483 • E-ISSN: 1096-8644
PublisherWiley (PUBLISHER • GB)
DOI10.1002/ajpa.1330550209
PMID7258343
OpenAlexW2077885480
LanguageEN
Citations received1
References cited20

Hemoglobin characteristics were investigated in 492 blood specimens collected in a small island community (1,450 inhabitants) in the Bahamas. Using two different methods, abnormal variants were detected in 20.3% of the sample, including genotypes AS, AC, AF(A/HPFH), SC, and SF. Biodemographic evidence suggests that the origin and distribution of the hemoglobinpathies in this population have been influenced by historical migrations and genetic drift. The opportunity for drift has been particularly heightened by the “founder effect,” the maintenance of small population size, a relatively endogamous mating structure, and restricted immigration. Health survey results reveal a wide discrepancy between the actual prevalence of abnormal hemoglobins and that indicated by informant reports

Geography · Hemoglobin · Hemoglobinopathies and Related Disorders · Internal Medicine · Medicine · Romani and Gypsy Studies

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