Leptin, adiposity, and testosterone in captive male macaques

Bibliographic Data

ID8319264
AuthorsMichael P Muehlenbein (0000-0003-1332-6264, University of Wisconsin–Milwaukee, corresponding author), B C Campbell (0000-0003-3497-3735, Boston University), Robert J Richards (0000-0003-2612-4063, Louisiana State University Health Sciences Center New Orleans), David P Watts (0000-0001-6603-2230, Yale University), Frank Svec (Louisiana State University Health Sciences Center New Orleans), Kathrine Phillippi Falkenstein, Mark A Murchison (Tulane University), Leann Myers (0000-0003-0333-7517, Tulane University)
Year2005
Volume127
Issue3
Pages335-341
Publication date2005-07-01
Peer ReviewedYes
Open AccessYes
TypeARTICLE
VenueAmerican Journal of Physical Anthropology (JOURNAL)
Journal identifiersISSN: 0002-9483 • E-ISSN: 1096-8644
PublisherWiley (PUBLISHER • GB)
DOI10.1002/ajpa.20071
PMID15558605
OpenAlexW2007664026
LanguageEN
Citations received5
References cited38

Leptin is considered to act as a signal relating somatic energetic status to the reproductive system. However, the nature of that signal and its relationship with male reproductive function across nonhuman primate species are unclear. We suggest that species-specific differences in leptin physiology may be related to the degree of environmental variation and variation in the importance of energy stores for male reproduction. In order to test the role of seasonality in species differences among nonhuman primates, we compared leptin, testosterone, and body composition in male rhesus (n = 69) and pig-tailed (n = 43) macaques. Despite having larger abdominal fat deposits, the rhesus macaques did not exhibit significantly higher leptin levels (rhesus, 2.21 +/- 0.43 ng/ml; pig-tailed, 2.12 +/- 0.39 ng/ml). Both species showed increases in leptin across adolescent, subadult, and adult age-groups (P = 0.036 for rhesus; P = 0.0003 for pig-tailed by ANCOVA). Testosterone was not significantly associated with leptin in either the rhesus (r = 0.039; P = 0.754) or pig-tailed (r = 0.2862; P = 0.066) samples. Comparison of leptin levels across the two species using univariate modeling procedures showed no significant age-group by abdominal fat interaction. These findings suggest little difference in leptin production between these two closely related species, despite the difference in breeding seasonality

Biology · Leptin · Obesity · Testosterone (patch) · Biochemical Analysis and Sensing Techniques · Endocrinology · Internal Medicine · Medicine · Regulation of Appetite and Obesity · Stress Responses and Cortisol

Tools

Open DOISci-Hub