Cytogenetic studies in the Hottentot population
Count distribution, report of a fragment, and preliminary description of morphology
Bibliographic Data
| ID | 8320580 |
|---|---|
| Authors | Paul G Heltne (University of Chicago), Ronald Singer (0000-0003-4915-3262, University of Chicago) |
| Year | 1971 |
| Volume | 34 |
| Issue | 1 |
| Pages | 1-35 |
| Publication date | 1971-01-01 |
| Peer Reviewed | Yes |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | American Journal of Physical Anthropology (JOURNAL) |
| Journal identifiers | ISSN: 0002-9483 • E-ISSN: 1096-8644 |
| Publisher | Wiley (PUBLISHER • GB) |
| DOI | 10.1002/ajpa.1330340102 |
| PMID | 5540493 |
| OpenAlex | W2147620866 |
| Language | EN |
| Citations received | 11 |
| References cited | 83 |
As part of a general investigation of the biology and morphological variation of the Hottentot population, this study deals with the karyotype analysis of a sample from that population. The modal number overall is 46; however, a high percentage of aneuploid cells, both hypomodal and hypermodal, is found. The rate of increase of aneuploidy with age is considered in detail. The rates for hypomodality with age for Hottentot females are positive and significantly higher than those for other populations previously reported. A fragment of chromatin is described. The fragment occurs in the two Hottentot males and in 22 of the 23 Hottentot females studied. Cells from the one non‐steatopygic female successfully cultured show fragments, as do cells from a Bushman female. In the Hottentots the average incidence of the single anomaly equals or exceeds the incidence of the total of all chromosome lesions in published studies giving control data. Metaphases from five individuals are figured, and several unusual features of the chromosomes are described. The findings are discussed in terms of functional integration at a cytological level karyotype pictures to be expected in hybridization between demes long isolated, and microevolution of the Hottentot population
Aneuploidy · Biology · Chromosome · Incidence (geometry) · Karyotype · Pathology · Population · Demography · Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities · Genetic Mapping and Diversity in Plants and Animals · Genetics · Medicine · Molecular Biology · Sperm and Testicular Function
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Brachymesophalangia V in Hottentot and “Cape Colored” children in Namibia (South West Africa) and South Africa
The development of genetics and population studies
History of physical anthropology in Southern Africa
Body height, weight, and skeletal maturation in Hottentot (Khoikhoi) children
Serology and clines along the Okavango River, Namibia
| Unique citing works | 11 |
|---|---|
| Citations per year | 0,21 |
| Citation span | 1974 - 1987 (14) |
| Citation velocity | historical |
| Highly cited | No |
| Citation types | Neutral: 11 |