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Provider Perspectives on Group PrEP Care for Sex Workers

A Pre-implementation Study in a U.S. Midwestern Community Health Center

Bibliographic Data

ID8355203
AuthorsRandi B Singer (0000-0001-9196-7812, Illinois College, corresponding author), Jessica Zemlak, Jessica L Zemlak (0000-0002-4770-5070, Marquette University), Sara Jacobs (0000-0002-0617-4285, Northwestern University), Natasha Crooks (0000-0003-0178-2844, University of Illinois Chicago), Oscar Daniel Bahena (University of Illinois Chicago), Maya Green (Skin Wellness Center), Susan G Sherman (0000-0001-8399-7544), S H Sherman (Johns Hopkins University), Geri R Donenberg (0000-0002-7925-0488, University of Illinois Chicago), Geri Donenberg, Alicia K Matthews (0000-0002-0074-681X, Columbia University), Crystal L Patil (0000-0003-4536-4599), Crystal Patil (University of Michigan)
Year2026
Publication date2026-01-04
Open AccessYes
TypeARTICLE
VenueArchives of Sexual Behavior (JOURNAL)
Journal identifiersISSN: 0004-0002 • E-ISSN: 1573-2800
PublisherSpringer Science and Business Media LLC (PUBLISHER)
DOI10.1007/s10508-025-03271-7
PMID41484542
OpenAlexW7118133538
LanguageEN
References cited63

Reducing new HIV infections is crucial. Sex workers continue to face disparities in both HIV infection rates and inadequate prevention care. Stigma, criminalization, and financial instability hinder access to vital HIV prevention methods, including Pre-exposure Prophylaxis (PrEP). Evidence-based, community-centered PrEP care may help address these issues. An evidence-based group PrEP care model, Centering PrEP (C-PrEP +), could empower communities and reduce healthcare burdens. This study explored care professionals’ perspectives on barriers and facilitators of C-PrEP + for sex workers. Using the Exploration, Preparation, Implementation, and Sustainment (EPIS) framework, we aimed to develop a pilot implementation plan for C-PrEP + . Individual interviews were held with care professionals at a U.S. Midwestern Community Health Center serving sex workers. To reflect the diverse roles and backgrounds of participants, we interviewed 14 healthcare professionals, including care providers, patient navigators, and billing specialists. Guided by a semi-structured interview guide, we sought care providers’ views on obstacles and enablers related to prescribing PrEP and implementing group PrEP care for sex workers. Using Dedoose, we used directed content analysis to systematically explore their perspectives about C-PrEP + using predefined constructs from the EPIS framework to guide coding and interpretation. Major themes included healthcare for sex workers, challenges in standard PrEP care, perceptions of Centering PrEP, and barriers and facilitators for implementing C-PrEP + . Participants viewed group PrEP care as a means to foster patient-centered approaches and strengthen community ties, while addressing the demands of care. Thoughtful integration of C-PrEP + into clinics may be a promising strategy to improve HIV prevention for sex workers

Community health center · Focus group · Health care · Human immunodeficiency virus (HIV) · Men who have sex with men · Pre-exposure prophylaxis · Public health · Qualitative research · HIV, Drug Use, Sexual Risk · HIV/AIDS Research and Interventions · Sex work and related issues

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Highly citedNo

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