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Variability in Pharmacy Interpretations of Physician Prescriptions

Bibliographic Data

ID9099525
AuthorsMichael S Wolf (0000-0002-4342-6517, Northwestern Medicine, corresponding author), Paul Shekelle (VA West Los Angeles Medical Center), Niteesh K Choudhry (0000-0001-7719-2248, Harvard University Press), Jessica Agnew-Blais (0000-0002-0755-6867, Harvard University Press), Ruth M Parker (0000-0001-9685-6396, Emory University), William H Shrank (Harvard University Press)
Year2009
Volume47
Issue3
Pages370-373
Publication date2009-03-01
Peer ReviewedYes
Open AccessNo
TypeARTICLE
VenueMedical Care (JOURNAL)
Journal identifiersISSN: 0025-7079 • E-ISSN: 1537-1948
PublisherOvid Technologies (Wolters Kluwer Health) (PUBLISHER)
DOI10.1097/mlr.0b013e31818af91a
PMID19194338
PMCIDPMC2680452
OpenAlexW2128460997
LanguageEN
Citations received6
References cited11

BACKGROUND: The clarity of prescription drug instructions is a health literacy and medication safety concern. OBJECTIVE: To assess the variability of pharmacy interpretations of physician prescriptions. DESIGN: Identically written prescriptions for 4 common medications (atorvastatin, alendronate, trimethoprim/sulfamethoxazole, ibuprofen) were filled in 6 pharmacies (2 largest chains, 2 grocery stores, 2 independents) in 4 cities (Boston, Chicago, Los Angeles, Austin). MEASUREMENT: Components of the instruction were coded as dose, frequency, administration route, timing, indication, and auxiliary instructions. RESULTS: In all, 85 labels were evaluated. Dose frequency was omitted on 6% of instructions ("take 1 tablet for cholesterol"). Timing was explicitly stated on 2% of instructions ("in the morning"). All prescriptions included indications; pharmacies transcribed these onto 38% of labels. The prescription for alendronate stated not to lie down for at least 30 minutes after taking; this was transcribed with 50% of instructions. Reading difficulty was above recommended levels for 46% of instructions; with 14% greater than a high school level. CONCLUSIONS: Efforts are needed to ensure patients receive clear, consistent information supporting safe medication use

Family medicine · Medical prescription · MEDLINE · Political science · Health Literacy and Information Accessibility · Medicine · Nursing · Pharmaceutical Practices and Patient Outcomes · Pharmacy · Safety Warnings and Signage

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Unique citing works6
Citations per year0,35
Citation span2009 - 2021 (13)
Citation velocityhistorical
Highly citedNo
Citation typesNeutral: 6

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