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Evaluating the Effect of Hospital and Insurance Type on the Risk of 1-year Mortality of Very Low Birth Weight Infants

Controlling for Selection Bias

Bibliographic Data

ID9100132
AuthorsSongthip Ounpraseuth (0000-0001-5623-0444, University of Arkansas for Medical Sciences, corresponding author), C Heath Gauss (0000-0001-9488-780X, University of Arkansas for Medical Sciences, corresponding author), Janet Bronstein (0000-0001-5365-0136, University of Alabama at Birmingham), Curtis Lowery, Curtis L Lowery (0000-0001-6027-6728, University of Arkansas for Medical Sciences), Richard Nugent (University of Arkansas for Medical Sciences), Richard W Hall (0000-0002-3264-3217, University of Arkansas for Medical Sciences), Richard Hall (0000-0001-7666-889X)
Year2012
Volume50
Issue4
Pages353-360
Publication date2012-04-01
Open AccessNo
TypeARTICLE
VenueMedical Care (JOURNAL)
Journal identifiersISSN: 0025-7079 • E-ISSN: 1537-1948
PublisherOvid Technologies (Wolters Kluwer Health) (PUBLISHER)
DOI10.1097/mlr.0b013e318245a128
PMID22422056
PMCIDPMC3306601
OpenAlexW2056605831
LanguageEN
Citations received1
References cited32

OBJECTIVES: We examined the effect of hospital type and medical coverage on the risk of 1-year mortality of very low birth weight (VLBW) infants while adjusting for possible selection bias. METHODS: The study population was limited to singleton live birth infants having birth weight between 500 and 1500 g with no congenital anomalies who were born in Arkansas hospitals between 2001 and 2007. Propensity score (PS) matching and PS covariate adjustment were used to mitigate selection bias. In addition, a conventional multivariable logistic regression model was used for comparison purposes. RESULTS: Generally, all 3 analytical approaches provided consistent results in terms of the estimated relative risk, absolute risk reduction, and the number needed to treat. Using the PS matching method, VLBW infants delivered at a hospital with a neonatal intensive care unit (NICU) were associated with a 35% relative decrease (95% bootstrap confidence interval, 18.5%-48.9%) in the risk of 1-year mortality as compared with those infants delivered at non-NICU hospitals. Furthermore, our results showed that on average, 16 VLBW infants (95% bootstrap confidence interval, 11-32), would need to be delivered at a hospital with an NICU to prevent 1 additional death at 1 year. However, there was not a difference in the risk of 1-year mortality between VLBW infants born to Medicaid-insured versus non-Medicaid-insured women. CONCLUSIONS: Estimated relative risk of infant mortality was significantly lower for births that occurred in hospitals with an NICU; therefore, greater efforts should be made to deliver VLBW neonates in an NICU hospital

Absolute risk reduction · Birth weight · Confidence interval · Environmental health · Health care · Infant mortality · Logistic regression · Low birth weight · Medicaid · Neonatal intensive care unit · Population · Pregnancy · Propensity score matching · Relative risk · Gestational Diabetes Research and Management · Internal Medicine · Maternal and Neonatal Healthcare · Medicine · Neonatal Respiratory Health Research · Surgery · Pediatrics

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Citations per year0.1
Citation span2016 - 2016 (1)
Highly citedNo

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