Measuring quality of life among HIV-infected women using a culturally adapted questionnaire in Rakai district, Uganda

Bibliographic Data

ID19443775
AuthorsT Christopher Mast (0000-0003-2396-7233, Johns Hopkins University, corresponding author), Godfrey Kigozi (0009-0008-9142-6870, Makerere University), F Wabwire-Mangen (c Institute of Public Health , Kampala), Fred Wabwire‐mangen (Institute of Public Health Bengaluru), R Black (0000-0003-4276-2057, a Department of International Health , Johns Hopkins University Bloomberg School of Public Health , MD , Baltimore), Robert E Black (0000-0001-9926-7984, Johns Hopkins University), Nelson K Sewankambo (0000-0001-9362-053X, Makerere University), N Sewankambo (b Makerere University , Kampala), David Serwadda (0000-0001-6532-6587, Makerere University), R Gray (0000-0001-6923-6183, d Department of Population Health and Family Sciences , Johns Hopkins University Bloomberg School of Public Health , MD , Baltimore), Ron E Gray (0000-0002-0512-063X, Johns Hopkins University), Maria J Wawer (0000-0002-3601-4469, Columbia University), M Wawer (Columbia University), Albert W Wu (0000-0001-6189-7120, Bloomberg (United States))
Year2004
Volume16
Issue1
Pages81-94
Publication date2004-01-01
Peer ReviewedYes
Open AccessNo
TypeARTICLE
VenueAIDS Care (JOURNAL)
Journal identifiersISSN: 0954-0121 • E-ISSN: 1360-0451
PublisherInforma UK Limited (PUBLISHER • GB)
DOI10.1080/09540120310001633994
PMID14660146
OpenAlexW2012551109
LanguageEN
Citations received45
References cited17

To examine self-reported quality of life and health status of HIV-infected women and a comparison sample of HIV-uninfected women in rural Uganda, we culturally adapted a Lugandan version of the Medical Outcomes Survey-HIV (MOS-HIV). We administered a cross-sectional survey among 803 women (239 HIV-positive and 564 HIV-negative) enrolled in a community study to evaluate maternal and child health in Rakai District, Uganda. The interview took 20 minutes and was generally well-accepted. Reliability coefficients were >0.70, except for role functioning, energy and cognitive function. MOS-HIV scores for HIV-positive women were correlated with increasing number of physical symptoms and higher HIV viral load. Compared to HIV-negative women, HIV-positive women reported lower scores than HIV-negative women for general health perceptions, physical functioning, pain, energy, role functioning, social functioning, mental health and overall quality of life (p all /=4 symptoms. In summary, HIV-positive women reported significantly poorer functioning and well-being than HIV-negative women. We conclude that patient-reported measures of health status and related concepts may provide a feasible, reliable and valid method to assess the impact of HIV/AIDS and future therapeutic interventions to improve patient outcomes in rural Africa

Cross-sectional study · Family medicine · Mental health · Psychiatry · Psychological intervention · Adolescent Sexual and Reproductive Health · Clinical Psychology · HIV-related health complications and treatments · HIV/AIDS Research and Interventions · Medicine · Nursing · Gerontology