Benefits of Home-Based Exercise Training Following Critical Sars-CoV-2 Infection

A Case Report

Datos Bibliográficos

ID5284655
AutoresIgor Longobardi (0000-0001-6669-9553), Danilo Marcelo Leite Do Prado (0000-0002-0321-2151), Karla Fabiana Goessler (0000-0002-5934-9819), Gersiel Nascimento De Oliveira Júnior (0000-0002-0803-2846), Danieli Castro Oliveira De Andrade, Danieli Andrade (0000-0002-0381-1808), Bruno Gualano (0000-0001-7100-8681), Hamilton Roschel (0000-0002-9513-6132)
Año2022
Volumen3
Páginas791703-791703
Fecha de publicación2022-01-11
Peer ReviewedSí
Open AccessSí
TipoARTICLE
RevistaFrontiers in Sports and Active Living (JOURNAL)
Identificadores de la revistaISSN: 2624-9367 • E-ISSN: 2624-9367
EditorialFrontiers Media SA (PUBLISHER • CH)
DOI10.3389/fspor.2021.791703
PMID35088048
OpenAlexW4206832627
IdiomaEN
Citas recibidas5
Referencias citadas32

In the current scenario, in which an elevated number of COVID-19 survivors present with severe physical deconditioning, exercise intolerance, persistent symptoms, and other post-acute consequences, effective rehabilitation strategies are of utmost relevance. In this study, we report for the first time the effect of home-based exercise training (HBET) in a survivor patient from critical COVID-19 illness. A 67-year-old woman who had critical COVID-19 disease [71 days of hospitalization, of which 49 days were in the intensive care unit (ICU) with invasive mechanical ventilation due to respiratory failure] underwent a 10-week HBET aiming to recovering overall physical condition. Before and after the intervention, we assessed cardiopulmonary parameters, skeletal muscle strength and functionality, fatigue severity, and self-reported persistent symptoms. At baseline (3 months after discharge), she presented with severe impairment in cardiorespiratory functional capacity (<50% age predicted VO2peak). After the intervention, remarkable improvements in VO2peak (from 10.61 to 15.48 mL·kg−1·min−1, Δ: 45.9%), oxygen uptake efficiency slope (OUES; from 1.0 to 1.3 L·min−1, Δ: 30.1%), HR/VO2 slope (from 92 to 52 bpm·L−1, Δ: −43.5%), the lowest VE/VCO2 ratio (from 35.4 to 32.9 L·min−1, Δ: −7.1%), and exertional dyspnea were observed. In addition, handgrip strength (from 22 to 27 kg, Δ: 22.7%), 30-s Sit-to-Stand (30-STS; from 14 to 16 repetitions, Δ:14.3%), Timed-Up-and-Go (TUG; from 8.25 to 7.01 s, Δ: −15%) performance and post-COVID functional status (PCFS) score (from 4 to 2) were also improved from baseline to post-intervention. Self-reported persistent symptoms were also improved, and Fatigue Severity Scale (FSS) score decreased (from 4 to 2.7) from baseline to post-intervention. This is the first evidence that a semi-supervised, HBET program may be safe and potentially effective in improving cardiorespiratory and physical functionality in COVID-19 survivors. Controlled studies are warranted to confirm these findings

Aerobic exercise · Blood pressure · Cardiology · Cardiorespiratory fitness · Deconditioning · Heart rate · Intensive care unit · Mechanical ventilation · Physical therapy · Respiratory minute volume · Respiratory system · Ventilation (architecture · VO2 max · Cardiovascular and exercise physiology · Intensive Care Unit Cognitive Disorders · Long-Term Effects of COVID-19 · Medicine · Internal Medicine