Mustafa Mahfuz
Biographic Data
| ID | 5466905 |
|---|---|
| NAME | Mustafa Mahfuz |
| GIVEN NAMES | Mustafa |
| FAMILY NAME | Mahfuz |
| SIGNATURE | MAHFUZ M |
| AFFILIATIONS | International Centre for Diarrhoeal Disease Research |
| ORCID | 0000-0002-4090-785X |
| VERIFIED | Yes |
| TOTAL WORKS | 21 |
| TOTAL CITATIONS | 1 |
| AUTHOR COUNT | 21 |
| EDITOR COUNT | 0 |
| FIRST PUBLICATION YEAR | 2016 |
| LATEST PUBLICATION YEAR | 2025 |
| H-INDEX | 1 |
Evolution of long Covid over two years in hospitalised and non-hospitalised survivors in Bangladesh
Background: In developing settings, comparative data on COVID hospitalised survivors (HS) and non-hospitalised survivors (NHS) is scarce. We determined burdens, incidence, evolution, and associated factors of long COVID-19 over two years among these groups. Methods: We conducted a longitudinal cohort study in Dhaka, Bangladesh, and recruited confirmed COVID-19 survivors from December 2020 to May 2021 (previously reported). 346 survivors underwent…
Prevalence and factors associated with undernutrition and overnutrition among ever-married adolescent girls in Bangladesh
Nutritional impairment during adolescence may result in adverse physical and reproductive health outcomes. We investigated the prevalence and determined the factors associated with underweight and overweight/obesity among ever-married adolescent girls in Bangladesh. We used Bangladesh Demographic and Health Surveys data conducted in 2004, 2007, 2011, 2014, and 2017. A total of 7040 ever-married adolescent girls aged 15–19 years were included in t…
Clinical characterisation, treatment outcomes, and case fatality risk of patients with different Sars-CoV-2 variants in Bangladesh
Background: Bangladesh underwent four waves of the coronavirus disease 2019 (COVID-19) pandemic. Analysing them is essential for understanding changes in viral behaviour, disease patterns, severity, and response to treatment. Nevertheless, data are scarce in low- and middle-income countries. Therefore, we aimed to compare clinical manifestations; outcomes for therapy with oxygen, dexamethasone, and remdesivir; as well as the case fatality during …
Geographical variation, socioeconomic inequalities of low birth weight, and its relationship with maternal dietary diversity
Background: Globally, every year, 20 million neonates are born with weights below 2500 g and are considered low birth weight (LBW). About 90% of these births occur in low- and middle-income countries. Information regarding the geographical variation, socioeconomic inequalities of LBW neonates, and the relationship between maternal inadequate dietary diversity and LBW is limited in rural areas of Bangladesh. We aimed to explore the geographical di…
Effect of Gut Microbiota-Directed Complementary Food Supplementation on Fecal and Plasma Biomarkers of Gut Health and Environmental Enteric Dysfunction in Slum-Dwelling Children with Moderate Acute Ma…
Dietary supplementation with a gut microbiota-directed complementary food (MDCF-2) significantly improved weight gain and repaired gut microbiota, as reported in a recent randomized controlled trial on Bangladeshi children with moderate acute malnutrition (MAM). Environmental enteric dysfunction (EED) is a small bowel disorder, and recent evidence shows that it is linked to growth failure in children. Therefore, we intended to investigate whether…
Food Safety Practices and Stunting among School-Age Children—An Observational Study Finding from an Urban Slum of Bangladesh
Background: Food safety incorporates the handling, preparation, and storage of food materials in ways that prevent foodborne illness. We aimed to investigate the typical food safety practices in a Bangladeshi slum context and to explore if stunting among school-age children was associated with various components of food safety. Method: We analysed the MAL-ED birth cohort data from the Bangladesh site. A total of 265 healthy children were enrolled…
Between and Within-Country Variations in Infant and Young Child Feeding Practices in South Asia
This study aimed to explore variations in Infant and Young Child Feeding (IYCF) practices between different South Asian Countries (SACs) and within their sociodemographic characteristics including place of residence, mother age, mother education, child sex, and wealth quintiles within the SACs. We extracted 0-23 months age children's data from the nationally representative survey of Afghanistan, Bangladesh, India, Maldives, Nepal, and Pakistan. A…
Characteristics associated with the transition to partial breastfeeding prior to 6 months of age
The WHO recommends exclusive breastfeeding for the first 6 months of life. However, the transition of the infants' diet to partial breastfeeding with the addition of animal milks and/or solids typically occurs earlier than this. Here, we explored factors associated with the timing of an early transition to partial breastfeeding across seven sites of a birth cohort study in which twice weekly information on infant feeding practices was collected. …
Influences on catch-up growth using relative versus absolute metrics
The study children demonstrated improved growth from 24 to 60 months of age, but only a subset had positive changes in HAD and WAD. The same environmental factors were associated with growth from 24 to 60 months regardless of metric used (change in HAZ or HAD, or WAZ and WAD)
Not water, sanitation and hygiene practice, but timing of stunting is associated with recovery from stunting at 24 months
Objectives: To measure the role of water, sanitation and hygiene (WASH) practices on recovery from stunting and assess the role of timing of stunting on the reversal of this phenomenon Design: Data from the MAL-ED multi-country birth cohort study was used for the current analysis. Generalised linear mixed-effects models were used to estimate the probability of reversal of stunting with WASH practice and timing of stunting as the exposures of inte…
Aflatoxin exposure was not associated with childhood stunting
Objective: Chronic aflatoxin exposure has been associated with childhood stunting (length-for-age/height-for-age sd ), while data lacks for Bangladesh, a country with substantial burden of childhood stunting. This paper examined the association between aflatoxin exposure and childhood stunting in a slum setting of Dhaka city. Design: In this MAL-ED aflatoxin birth cohort study, plasma samples were assayed for aflatoxin B1-lysine adduct (AFB1-lys)…
Topical emollient therapy in the management of severe acute malnutrition in children under two
BACKGROUND: Topical emollient therapy can improve neonatal health and growth and potentially provides an additional avenue for augmenting the provision of nutrition to children with severe acute malnutrition (SAM). We hypothesised that topical treatment of hospitalised children with SAM using sunflower seed oil (SSO), in addition to standard-of-care for SAM, would improve skin barrier function and weight gain, reduce risk of infection, and accele…
Proof-of-concept study of the efficacy of a microbiota-directed complementary food formulation (MDCF) for treating moderate acute malnutrition
The primary MAM and post-SAM MAM trials are registered in Clintrials.gov (NCT04015999 and NCT04015986, registered on July 11, 2019, retrospectively registered)
Early childhood development and stunting
Information on the association between stunting and child development is limited from low-income settings including Bangladesh where 36% of children under- 5 are stunted. This study aimed to explore differences in early childhood development (ECD) between stunted (length-for-age z-score [LAZ] < -2) and nonstunted (LAZ ≥ -2) children in Bangladesh. Children (n = 265) aged 6-24 months who participated in the MAL-ED birth cohort study were evaluated…
Prevalence and sociodemographic determinants of household-level double burden of malnutrition in Bangladesh
Objective To investigate the prevalence and sociodemographic determinants of household-level mother–child double burden (MCDB) of malnutrition in Bangladesh. Design The analysis was done using Bangladesh Demographic and Health Survey 2014 data. Multivariable logistic regression identified the sociodemographic factors associated with double-burden households. Setting Nationally representative cross-sectional survey. Participants A total of 5951 ho…
Development and validation of a tool to assess appetite of children in low income settings
Risk factors of stunting among children living in an urban slum of Bangladesh
As the mechanism of stunting begins even before a child is born, strategies must be focused on life course approach and preventive measurement should be initiated during pregnancy. Alongside, government and policymakers have to develop sustainable strategies to improve various social and environmental factors those are closely interrelated with chronic undernutrition particularly concentrating on urban slum areas
Caregiver perceptions of children’s linear growth in Bangladesh
Objective To understand caregivers’ perceptions of children’s linear growth and to identify the cultural meanings and perceptions of risk associated with poor height attainment. Design Three investigators from Bangladesh conducted twelve focus group discussions. Setting The study was conducted in rural and slum settings in Bangladesh. Subjects Participants included mothers and alternative caregivers ( n 81) who were recruited by household screeni…
“Those who care much, understand much.” Maternal perceptions of children's appetite
Appetite in children is an important determinant of nutritional intake and growth. The information used by caregivers to understand children's appetite can help inform infant and young child feeding promotion and appetite assessment. We conducted a qualitative study to (a) explore maternal perceptions and responses to children's appetite and (b) to identify how these factors differ by type of caregiver, level of maternal experience, and urban ver…
Prevalence and risk factors of vitamin D insufficiency and deficiency among 6–24-month-old underweight and normal-weight children living in an urban slum of Bangladesh
Objective We quantified the prevalence of vitamin D status in 6–24-month-old underweight and normal-weight children and identified the socio-economic and dietary predictors for status. Design Cross-sectional, baseline data from a nutritional intervention study were analysed. Multinomial logistic regression was used to estimate the odds of being vitamin D deficient or insufficient with the reference being vitamin D sufficient. Setting Urban slum a…
Imperatives for reducing child stunting in Bangladesh
Although there has been a decline in rates of child stunting in Bangladesh, more than one-third of under-five children still suffer from impaired linear growth. Results of the demographic health surveys since 2004 show that the rate of stunting decreased by only 1.5 percentage points per year (NIPORT, Mitra and Associates & ICF International, 2015). This is not anticipated, given the impressive results the country has demonstrated in reducing inf…
Imperatives for reducing child stunting in Bangladesh
Although there has been a decline in rates of child stunting in Bangladesh, more than one-third of under-five children still suffer from impaired linear growth. Results of the demographic health surveys since 2004 show that the rate of stunting decreased by only 1.5 percentage points per year (NIPORT, Mitra and Associates & ICF International, 2015). This is not anticipated, given the impressive results the country has demonstrated in reducing inf…
“Those who care much, understand much.” Maternal perceptions of children's appetite
Appetite in children is an important determinant of nutritional intake and growth. The information used by caregivers to understand children's appetite can help inform infant and young child feeding promotion and appetite assessment. We conducted a qualitative study to (a) explore maternal perceptions and responses to children's appetite and (b) to identify how these factors differ by type of caregiver, level of maternal experience, and urban ver…
Prevalence and risk factors of vitamin D insufficiency and deficiency among 6–24-month-old underweight and normal-weight children living in an urban slum of Bangladesh
Objective We quantified the prevalence of vitamin D status in 6–24-month-old underweight and normal-weight children and identified the socio-economic and dietary predictors for status. Design Cross-sectional, baseline data from a nutritional intervention study were analysed. Multinomial logistic regression was used to estimate the odds of being vitamin D deficient or insufficient with the reference being vitamin D sufficient. Setting Urban slum a…
Risk factors of stunting among children living in an urban slum of Bangladesh
As the mechanism of stunting begins even before a child is born, strategies must be focused on life course approach and preventive measurement should be initiated during pregnancy. Alongside, government and policymakers have to develop sustainable strategies to improve various social and environmental factors those are closely interrelated with chronic undernutrition particularly concentrating on urban slum areas
Caregiver perceptions of children’s linear growth in Bangladesh
Objective To understand caregivers’ perceptions of children’s linear growth and to identify the cultural meanings and perceptions of risk associated with poor height attainment. Design Three investigators from Bangladesh conducted twelve focus group discussions. Setting The study was conducted in rural and slum settings in Bangladesh. Subjects Participants included mothers and alternative caregivers ( n 81) who were recruited by household screeni…
Early childhood development and stunting
Information on the association between stunting and child development is limited from low-income settings including Bangladesh where 36% of children under- 5 are stunted. This study aimed to explore differences in early childhood development (ECD) between stunted (length-for-age z-score [LAZ] < -2) and nonstunted (LAZ ≥ -2) children in Bangladesh. Children (n = 265) aged 6-24 months who participated in the MAL-ED birth cohort study were evaluated…
Prevalence and sociodemographic determinants of household-level double burden of malnutrition in Bangladesh
Objective To investigate the prevalence and sociodemographic determinants of household-level mother–child double burden (MCDB) of malnutrition in Bangladesh. Design The analysis was done using Bangladesh Demographic and Health Survey 2014 data. Multivariable logistic regression identified the sociodemographic factors associated with double-burden households. Setting Nationally representative cross-sectional survey. Participants A total of 5951 ho…
Development and validation of a tool to assess appetite of children in low income settings
Topical emollient therapy in the management of severe acute malnutrition in children under two
BACKGROUND: Topical emollient therapy can improve neonatal health and growth and potentially provides an additional avenue for augmenting the provision of nutrition to children with severe acute malnutrition (SAM). We hypothesised that topical treatment of hospitalised children with SAM using sunflower seed oil (SSO), in addition to standard-of-care for SAM, would improve skin barrier function and weight gain, reduce risk of infection, and accele…
Proof-of-concept study of the efficacy of a microbiota-directed complementary food formulation (MDCF) for treating moderate acute malnutrition
The primary MAM and post-SAM MAM trials are registered in Clintrials.gov (NCT04015999 and NCT04015986, registered on July 11, 2019, retrospectively registered)
Characteristics associated with the transition to partial breastfeeding prior to 6 months of age
The WHO recommends exclusive breastfeeding for the first 6 months of life. However, the transition of the infants' diet to partial breastfeeding with the addition of animal milks and/or solids typically occurs earlier than this. Here, we explored factors associated with the timing of an early transition to partial breastfeeding across seven sites of a birth cohort study in which twice weekly information on infant feeding practices was collected. …
Influences on catch-up growth using relative versus absolute metrics
The study children demonstrated improved growth from 24 to 60 months of age, but only a subset had positive changes in HAD and WAD. The same environmental factors were associated with growth from 24 to 60 months regardless of metric used (change in HAZ or HAD, or WAZ and WAD)
Not water, sanitation and hygiene practice, but timing of stunting is associated with recovery from stunting at 24 months
Objectives: To measure the role of water, sanitation and hygiene (WASH) practices on recovery from stunting and assess the role of timing of stunting on the reversal of this phenomenon Design: Data from the MAL-ED multi-country birth cohort study was used for the current analysis. Generalised linear mixed-effects models were used to estimate the probability of reversal of stunting with WASH practice and timing of stunting as the exposures of inte…
Aflatoxin exposure was not associated with childhood stunting
Objective: Chronic aflatoxin exposure has been associated with childhood stunting (length-for-age/height-for-age sd ), while data lacks for Bangladesh, a country with substantial burden of childhood stunting. This paper examined the association between aflatoxin exposure and childhood stunting in a slum setting of Dhaka city. Design: In this MAL-ED aflatoxin birth cohort study, plasma samples were assayed for aflatoxin B1-lysine adduct (AFB1-lys)…
Food Safety Practices and Stunting among School-Age Children—An Observational Study Finding from an Urban Slum of Bangladesh
Background: Food safety incorporates the handling, preparation, and storage of food materials in ways that prevent foodborne illness. We aimed to investigate the typical food safety practices in a Bangladeshi slum context and to explore if stunting among school-age children was associated with various components of food safety. Method: We analysed the MAL-ED birth cohort data from the Bangladesh site. A total of 265 healthy children were enrolled…
Between and Within-Country Variations in Infant and Young Child Feeding Practices in South Asia
This study aimed to explore variations in Infant and Young Child Feeding (IYCF) practices between different South Asian Countries (SACs) and within their sociodemographic characteristics including place of residence, mother age, mother education, child sex, and wealth quintiles within the SACs. We extracted 0-23 months age children's data from the nationally representative survey of Afghanistan, Bangladesh, India, Maldives, Nepal, and Pakistan. A…
Prevalence and factors associated with undernutrition and overnutrition among ever-married adolescent girls in Bangladesh
Nutritional impairment during adolescence may result in adverse physical and reproductive health outcomes. We investigated the prevalence and determined the factors associated with underweight and overweight/obesity among ever-married adolescent girls in Bangladesh. We used Bangladesh Demographic and Health Surveys data conducted in 2004, 2007, 2011, 2014, and 2017. A total of 7040 ever-married adolescent girls aged 15–19 years were included in t…
Clinical characterisation, treatment outcomes, and case fatality risk of patients with different Sars-CoV-2 variants in Bangladesh
Background: Bangladesh underwent four waves of the coronavirus disease 2019 (COVID-19) pandemic. Analysing them is essential for understanding changes in viral behaviour, disease patterns, severity, and response to treatment. Nevertheless, data are scarce in low- and middle-income countries. Therefore, we aimed to compare clinical manifestations; outcomes for therapy with oxygen, dexamethasone, and remdesivir; as well as the case fatality during …
Geographical variation, socioeconomic inequalities of low birth weight, and its relationship with maternal dietary diversity
Background: Globally, every year, 20 million neonates are born with weights below 2500 g and are considered low birth weight (LBW). About 90% of these births occur in low- and middle-income countries. Information regarding the geographical variation, socioeconomic inequalities of LBW neonates, and the relationship between maternal inadequate dietary diversity and LBW is limited in rural areas of Bangladesh. We aimed to explore the geographical di…
Effect of Gut Microbiota-Directed Complementary Food Supplementation on Fecal and Plasma Biomarkers of Gut Health and Environmental Enteric Dysfunction in Slum-Dwelling Children with Moderate Acute Ma…
Dietary supplementation with a gut microbiota-directed complementary food (MDCF-2) significantly improved weight gain and repaired gut microbiota, as reported in a recent randomized controlled trial on Bangladeshi children with moderate acute malnutrition (MAM). Environmental enteric dysfunction (EED) is a small bowel disorder, and recent evidence shows that it is linked to growth failure in children. Therefore, we intended to investigate whether…
Evolution of long Covid over two years in hospitalised and non-hospitalised survivors in Bangladesh
Background: In developing settings, comparative data on COVID hospitalised survivors (HS) and non-hospitalised survivors (NHS) is scarce. We determined burdens, incidence, evolution, and associated factors of long COVID-19 over two years among these groups. Methods: We conducted a longitudinal cohort study in Dhaka, Bangladesh, and recruited confirmed COVID-19 survivors from December 2020 to May 2021 (previously reported). 346 survivors underwent…
Medicine (21 works) · Child Nutrition and Water Access (17 works) · Pediatrics (15 works) · Demography (12 works) · Environmental health (12 works) · Internal Medicine (12 works) · Demography (9 works) · Child Nutrition and Feeding Issues (7 works) · Cohort (7 works) · Malnutrition (7 works)