Lingli Zhang
Biographic Data
| ID | 7092534 |
|---|---|
| NAME | Lingli Zhang |
| GIVEN NAMES | Lingli |
| FAMILY NAME | Zhang |
| SIGNATURE | ZHANG L |
| AFFILIATIONS | National Medical Products Administration |
| ORCID | 0000-0003-1407-8098 |
| VERIFIED | Yes |
| TOTAL WORKS | 22 |
| TOTAL CITATIONS | 0 |
| AUTHOR COUNT | 22 |
| EDITOR COUNT | 0 |
| FIRST PUBLICATION YEAR | 2010 |
| LATEST PUBLICATION YEAR | 2026 |
| H-INDEX | 0 |
Temporal trend and influencing factors of high-risk pregnancy in China
Background High-risk pregnancy was a major challenge to sustainably reduce maternal mortality rate to achieve the Sustainable Development Goals in China. This study aimed to analyze the temporal trend of high-risk pregnancy rate in China and to explore the influence of socioeconomic factors. Methods Panel data of 31 provinces in China from 2002 to 2016 were extracted from the China Statistical Yearbooks and Health Statistical Yearbooks. We firstl…
Generation pathways of innovation capability among engineering graduate students at Chinese Double First-Class universities
Innovation capability at the graduate level is a key outcome of higher education, reflecting not only institutional arrangements but also students' learning-related psychological processes. As China has become a major global hub for engineering education, understanding how engineering graduate students develop innovation capability is essential for cultivating high-level innovative talent. However, existing studies have largely relied on variable…
Tension and adaptation under the indicator-based governance
How to alleviate the shortage
Drug shortages have been reported to lead to insufficient treatment, delays or cancellations in care, poor medication adherence, prolonged hospital stays, increased medication errors, adverse events related to alternative therapies, and even deaths, posing a serious threat to public health. Despite ongoing and substantial efforts to address this issue, many drug shortages continue to persist. Against this backdrop, this study aims to conduct a sc…
Impact of hospital payment reform on rational use of antibiotics
Introduction: While numerous studies have examined the effects of diagnosis-related groups (DRG) payment on hospital healthcare, evidence regarding its impact on the quality of hospital healthcare is poor and findings have been inconsistent. This study evaluates how DRG payment reform influences rational use of antibiotics in hospital using the World Health Organization (WHO) Access, Watch, Reserve (AWaRe) classification in China. Methods: We emp…
Characteristics of indications, clinical trial evidence, clinical benefits and the costs of price-negotiated multi-indication drugs for solid tumours in China
Background: Cancer is a leading cause of death globally, with China accounting for a significant portion of new cases and deaths. The Government of China has introduced the National Drug Price Negotiation (NDPN) policy to mitigate the high costs of anticancer drugs, especially multi-indication drugs, aimed at improving patient access to effective treatments. Methods: In this retrospective study, we examined 24 multi-indication anticancer drugs fo…
A survey of availability, price, and affordability of innovative negotiated anticancer medicines
The accessibility of INAMs improved from 2020 to 2022. However, the accessibility of INAMs is influenced by various factors, and disparities still exist in access across different healthcare institutions and between urban and rural areas. Effective and sustainable policies need to be developed to ensure equitable access to medicines for all patients
The macroeconomic burden of hepatitis C and the economic benefit of accelerated investments in China
Achieving the WHO Global Health Sector Strategy diagnosis and treatment coverage targets by 2030 in China is projected to be cost-effective and result in significant health and economic benefits. The findings underscore the importance of increased investment in hepatitis C elimination efforts in China
Patient versus physician preferences for lipid‐lowering drug therapy
BACKGROUND: The emergence of proprotein convertase subtilisin/kexin type 9 inhibitors offered dyslipidemia patients an alternative to statins for lipid-lowering treatment. Understanding patient and physician preferences for lipid-lowering drugs may promote shared decision-making and improve treatment outcomes. METHODS: This study utilized an online discrete choice experiment (DCE) to assess the relative importance (RI) of six attributes related t…
Impact of national drug price negotiation policy on the accessibility and utilization of PCSK9 inhibitors in China
The NDPN policy has successfully improved the accessibility and utilization of PCSK9 inhibitors in China. However, regional disparities in utilization indicate the need for further interventions to ensure equitable medicine access
Availability of essential medicines, progress and regional distribution in China
Recombinant mycobacterium tuberculosis fusion protein for diagnosis of mycobacterium tuberculosis infection
Objectives: Recombinant Mycobacterium tuberculosis fusion protein (EC) was anticipated to be used for the scale-up of clinical application for diagnosis of Mycobacterium tuberculosis infection in China, but it lacked a head-to-head economic evaluation based on the Chinese population. This study aimed to estimate the cost-utility and the cost-effectiveness of both EC and tuberculin pure protein derivative (TB-PPD) for diagnosis of Mycobacterium tu…
Shyness and Socio-emotional Adjustment Difficulties in Urban Chinese Kindergartners
Research Findings: The goal of the present study was to examine the moderating role of child effortful control (EC) in the relation between shyness and social-emotional adjustment difficulties among young Chinese children. Participants included 195 children (117 boys, 78 girls, Mage = 4.28 years, SD = 0.31) enrolled in 6 classes attending kindergartens, Shanghai, People’s Republic of China. Mothers provided ratings of their children’s temperament…
Degarelix vs. leuprorelin for the treatment of prostate cancer in China
Objective: To explore the cost-effectiveness of degarelix acetate for injection (degarelix) compared to leuprorelin in prostate cancer (Pca) castration treatment from Chinese healthcare system perspective. Methods: A Markov model, adapted from the one established in Finland was conducted for the cost-effectiveness analysis of degarelix and leuprorelin for Pca treatment. The main data were derived from global phase III clinical trials of degarelix…
Hepatitis B Infection Among Pregnant Women in China
Accessibility of essential anticancer medicines for children in the Sichuan Province of China
Background: Compared with high-income countries, the survival rate of childhood cancer is lower in low- and middle-income countries. Access to essential anticancer medicines is an indispensable component of pediatric cancer treatment, which is still a big challenge in low- and middle-income countries. Objective: To assess the accessibility of essential anticancer medicines for children in public hospitals in the Sichuan Province of China. Methods…
Effectiveness of Online-Delivered Project ImPact for Children With ASD and Their Parents
The 8-week, online-delivered Project ImPACT program is a feasible and effective social skill training program for families of children with ASD in China during the COVID-19 pandemic. Due to the methodological limitations, randomized controlled studies with larger sample sizes are suggested to provide more solid evidence
Temporopolar volumes are associated with the severity of social impairment and language development in children with autism spectrum disorder with developmental delay
In this study, we found that temporopolar volumes were enlarged in patients with ASD who had comorbid DD, and these patients showed an association between symptom severity and language ability during the pre-language stage. Offering early interventions focused on RJA and the temporal pole may help improve clinical symptoms
From child social impairment to parenting stress in mothers of children with ASD
Future early intervention programs that focused on child's social communication skills and empowered mothers with related strategies through group-based parent training programs may help reduce parenting stress
Development of the Chinese preschooler dietary index
The CPDI is useful in evaluating the diet quality of preschool children. Based on the CPDI, the diet quality of Chinese preschoolers needs to be improved, especially in rural areas
Gut Microbial Profile Is Associated With the Severity of Social Impairment and IQ Performance in Children With Autism Spectrum Disorder
Background and Objective: Autism spectrum disorder (ASD) refers to a heterogeneous set of neurodevelopmental disorders with diverse symptom severity and comorbidities. Although alterations in gut microbiota have been reported in individuals with ASD, it remains unclear whether certain microbial pattern is linked to specific symptom or comorbidity in ASD. We aimed to investigate the associations between gut microbiota and the severity of social im…
Nutrition knowledge, attitudes, behaviours and the influencing factors among non-parent caregivers of rural left-behind children under 7 years old in China
Objective To explore and compare nutrition knowledge, attitudes and behaviours (KAB) between non-parent and parent caregivers of children under 7 years old in Chinese rural areas, and to identify the factors influencing their nutrition KAB. Design Face-to-face interviews were carried out with 1691 non-parent caregivers and 1670 parent caregivers in the selected study areas; multivariate logistic regression models were used to identify the factors…
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Nutrition knowledge, attitudes, behaviours and the influencing factors among non-parent caregivers of rural left-behind children under 7 years old in China
Objective To explore and compare nutrition knowledge, attitudes and behaviours (KAB) between non-parent and parent caregivers of children under 7 years old in Chinese rural areas, and to identify the factors influencing their nutrition KAB. Design Face-to-face interviews were carried out with 1691 non-parent caregivers and 1670 parent caregivers in the selected study areas; multivariate logistic regression models were used to identify the factors…
Gut Microbial Profile Is Associated With the Severity of Social Impairment and IQ Performance in Children With Autism Spectrum Disorder
Background and Objective: Autism spectrum disorder (ASD) refers to a heterogeneous set of neurodevelopmental disorders with diverse symptom severity and comorbidities. Although alterations in gut microbiota have been reported in individuals with ASD, it remains unclear whether certain microbial pattern is linked to specific symptom or comorbidity in ASD. We aimed to investigate the associations between gut microbiota and the severity of social im…
Degarelix vs. leuprorelin for the treatment of prostate cancer in China
Objective: To explore the cost-effectiveness of degarelix acetate for injection (degarelix) compared to leuprorelin in prostate cancer (Pca) castration treatment from Chinese healthcare system perspective. Methods: A Markov model, adapted from the one established in Finland was conducted for the cost-effectiveness analysis of degarelix and leuprorelin for Pca treatment. The main data were derived from global phase III clinical trials of degarelix…
Hepatitis B Infection Among Pregnant Women in China
Accessibility of essential anticancer medicines for children in the Sichuan Province of China
Background: Compared with high-income countries, the survival rate of childhood cancer is lower in low- and middle-income countries. Access to essential anticancer medicines is an indispensable component of pediatric cancer treatment, which is still a big challenge in low- and middle-income countries. Objective: To assess the accessibility of essential anticancer medicines for children in public hospitals in the Sichuan Province of China. Methods…
Effectiveness of Online-Delivered Project ImPact for Children With ASD and Their Parents
The 8-week, online-delivered Project ImPACT program is a feasible and effective social skill training program for families of children with ASD in China during the COVID-19 pandemic. Due to the methodological limitations, randomized controlled studies with larger sample sizes are suggested to provide more solid evidence
Temporopolar volumes are associated with the severity of social impairment and language development in children with autism spectrum disorder with developmental delay
In this study, we found that temporopolar volumes were enlarged in patients with ASD who had comorbid DD, and these patients showed an association between symptom severity and language ability during the pre-language stage. Offering early interventions focused on RJA and the temporal pole may help improve clinical symptoms
From child social impairment to parenting stress in mothers of children with ASD
Future early intervention programs that focused on child's social communication skills and empowered mothers with related strategies through group-based parent training programs may help reduce parenting stress
Development of the Chinese preschooler dietary index
The CPDI is useful in evaluating the diet quality of preschool children. Based on the CPDI, the diet quality of Chinese preschoolers needs to be improved, especially in rural areas
Availability of essential medicines, progress and regional distribution in China
Recombinant mycobacterium tuberculosis fusion protein for diagnosis of mycobacterium tuberculosis infection
Objectives: Recombinant Mycobacterium tuberculosis fusion protein (EC) was anticipated to be used for the scale-up of clinical application for diagnosis of Mycobacterium tuberculosis infection in China, but it lacked a head-to-head economic evaluation based on the Chinese population. This study aimed to estimate the cost-utility and the cost-effectiveness of both EC and tuberculin pure protein derivative (TB-PPD) for diagnosis of Mycobacterium tu…
Shyness and Socio-emotional Adjustment Difficulties in Urban Chinese Kindergartners
Research Findings: The goal of the present study was to examine the moderating role of child effortful control (EC) in the relation between shyness and social-emotional adjustment difficulties among young Chinese children. Participants included 195 children (117 boys, 78 girls, Mage = 4.28 years, SD = 0.31) enrolled in 6 classes attending kindergartens, Shanghai, People’s Republic of China. Mothers provided ratings of their children’s temperament…
Patient versus physician preferences for lipid‐lowering drug therapy
BACKGROUND: The emergence of proprotein convertase subtilisin/kexin type 9 inhibitors offered dyslipidemia patients an alternative to statins for lipid-lowering treatment. Understanding patient and physician preferences for lipid-lowering drugs may promote shared decision-making and improve treatment outcomes. METHODS: This study utilized an online discrete choice experiment (DCE) to assess the relative importance (RI) of six attributes related t…
Impact of national drug price negotiation policy on the accessibility and utilization of PCSK9 inhibitors in China
The NDPN policy has successfully improved the accessibility and utilization of PCSK9 inhibitors in China. However, regional disparities in utilization indicate the need for further interventions to ensure equitable medicine access
Impact of hospital payment reform on rational use of antibiotics
Introduction: While numerous studies have examined the effects of diagnosis-related groups (DRG) payment on hospital healthcare, evidence regarding its impact on the quality of hospital healthcare is poor and findings have been inconsistent. This study evaluates how DRG payment reform influences rational use of antibiotics in hospital using the World Health Organization (WHO) Access, Watch, Reserve (AWaRe) classification in China. Methods: We emp…
Characteristics of indications, clinical trial evidence, clinical benefits and the costs of price-negotiated multi-indication drugs for solid tumours in China
Background: Cancer is a leading cause of death globally, with China accounting for a significant portion of new cases and deaths. The Government of China has introduced the National Drug Price Negotiation (NDPN) policy to mitigate the high costs of anticancer drugs, especially multi-indication drugs, aimed at improving patient access to effective treatments. Methods: In this retrospective study, we examined 24 multi-indication anticancer drugs fo…
A survey of availability, price, and affordability of innovative negotiated anticancer medicines
The accessibility of INAMs improved from 2020 to 2022. However, the accessibility of INAMs is influenced by various factors, and disparities still exist in access across different healthcare institutions and between urban and rural areas. Effective and sustainable policies need to be developed to ensure equitable access to medicines for all patients
The macroeconomic burden of hepatitis C and the economic benefit of accelerated investments in China
Achieving the WHO Global Health Sector Strategy diagnosis and treatment coverage targets by 2030 in China is projected to be cost-effective and result in significant health and economic benefits. The findings underscore the importance of increased investment in hepatitis C elimination efforts in China
Temporal trend and influencing factors of high-risk pregnancy in China
Background High-risk pregnancy was a major challenge to sustainably reduce maternal mortality rate to achieve the Sustainable Development Goals in China. This study aimed to analyze the temporal trend of high-risk pregnancy rate in China and to explore the influence of socioeconomic factors. Methods Panel data of 31 provinces in China from 2002 to 2016 were extracted from the China Statistical Yearbooks and Health Statistical Yearbooks. We firstl…
Generation pathways of innovation capability among engineering graduate students at Chinese Double First-Class universities
Innovation capability at the graduate level is a key outcome of higher education, reflecting not only institutional arrangements but also students' learning-related psychological processes. As China has become a major global hub for engineering education, understanding how engineering graduate students develop innovation capability is essential for cultivating high-level innovative talent. However, existing studies have largely relied on variable…
Tension and adaptation under the indicator-based governance
How to alleviate the shortage
Drug shortages have been reported to lead to insufficient treatment, delays or cancellations in care, poor medication adherence, prolonged hospital stays, increased medication errors, adverse events related to alternative therapies, and even deaths, posing a serious threat to public health. Despite ongoing and substantial efforts to address this issue, many drug shortages continue to persist. Against this backdrop, this study aims to conduct a sc…
Medicine (15 works) · China (8 works) · Environmental health (7 works) · Psychology (7 works) · Internal Medicine (5 works) · Pharmaceutical Economics and Policy (5 works) · Autism (4 works) · Autism spectrum disorder (4 works) · Autism Spectrum Disorder Research (4 works) · Biostatistics (4 works)