Christina Warinner
Datos Biográficos
| ID | 92292 |
|---|---|
| NOMBRE | Christina Warinner |
| NOMBRES | Christina |
| APELLIDO | Warinner |
| FIRMA | WARINNER C |
| AFILIACIONES | Harvard University |
| ORCID | 0000-0002-4528-5877 |
| VERIFICADO | Sí |
| TOTAL DE OBRAS | 31 |
| TOTAL DE CITAS | 245 |
| TOTAL COMO AUTOR | 31 |
| TOTAL COMO EDITOR | 0 |
| PRIMER AÑO DE PUBLICACIÓN | 2009 |
| AÑO MÁS RECIENTE DE PUBLICACIÓN | 2026 |
| ÍNDICE H | 8 |
The Oral Microbiome of King Richard III of England
Applying demographic and epidemiological models in challenging situations
OBJECTIVE: To demonstrate the utility of applying demographic and epidemiological models to assess the potential effects of sociopolitical status and childhood stress on survivorship, mortality, and morbidity to shed new light on life during the Maya Classic period. MATERIALS: Elite and commoner burials (n = 63) from the Lower Dover polity, Belize dating to the Early (CE 250/300-600) and Late/Terminal Classic (CE 600-900/1000) periods were analyz…
Changing the Landscape of Archaeological Publishing
Disseminating research is a key component of scholarly labor, but the costs and benefits of the current structure of academic publishing are underexamined within anthropology. This paper brings together a range of authors from across archaeology and cultural anthropology to summarize current issues in archaeological publishing and offer potential interventions at multiple scales. The paper is divided into five core topics. “Ideology” discusses th…
Author response of
A recommendation of: Joannes A. A. Dekker, Carli Peters, Rachel M. Winter, Matthew J. Collins, Marc R. Dickinson, Virginia L. Harvey, Eden Hill, Bharath Nair, Takumi Tsutaya, Laura C. Viñas- Caron, Christina Warinner, Frido Welker, Zandra Fagernäs Open science, communication, and collaboration for the future of palaeoproteomics https://doi.org/10.5281/zenodo.15546095
Biocultural Taphonomies and Analysis of an Emerging Terminal Classic (750–900 CE) Maya Deathway
In bioarchaeology, funerary taphonomy and preservation become part of the biocultural narrative of the dead. We evaluate the role of these factors in reconstructing the identities of those buried in an emerging deathway, the ventrally placed legs flexed (VPLF) burial position, during the Terminal Classic (750–900/1000 CE) period at the Maya polity of Lower Dover in western Belize. The term “VPLF” describes a divergent burial practice which may ha…
The origins of saddles and riding technology in East Asia
Innovations in horse equipment during the early Middle Ages provided advantages to societies from the steppes, reshaping the social landscape of Eurasia. Comparatively little is known about the precise origin of these crucial advances, although the available evidence points to early adoption in East Asia. The authors present new archaeological discoveries from western and northern Mongolia, dating to the fourth and fifth centuries AD, including a…
Your horse is a donkey! Identifying domesticated equids from Western Iberia using collagen fingerprinting
Skeletal remains of two equid species, Equus caballus (horse) and Equus asinus (donkey), have been found in archaeological contexts throughout Iberia since the Palaeolithic and Chalcolithic periods, respectively. These two species play different economic and cultural roles, and therefore it is important to be able to distinguish between the two species to better understand their relative importance in the past human societies. The most reliable m…
An Archaeology of Microbes
Humans have a deep and complex relationship with microbes. Beyond disease, microbes also profoundly shape human health and behavior through their activity in the microbiome and their diverse roles in food and cuisine. And yet we know very little about the origin, evolution, or ecology of the trillions of microorganisms that call us home. Recent advances in genomic and proteomic technologies are opening up dramatic new opportunities in the field o…
Evidence for early dispersal of domestic sheep into Central Asia
Enduring Cycles
In this photo essay we elaborate on artisanal dairying practices in the European Alps and Mongolia. By comparing these geographically distant dairying practices, we view milk fermentation as a multispecies, multidomain food ecology that links bacteria, fungi, plants, animals, and humans in unbroken cycles of production and reproduction that have endured for millennia. We focus on how peasant dairy producers actively engage with microbial communit…
Cultures of Fermentation
Recent discoveries on the importance of microbes for human biology, health, and culture, the rise of antimicrobial resistance, and developing technological advancements necessitate new dialogues about human relationships with microbes. Long perceptible only through their transformations-from epidemic disease to alcoholic beverages-it is now possible to more fully perceive the diversity of ways in which we influence and are influenced by microbes …
A unified protocol for simultaneous extraction of DNA and proteins from archaeological dental calculus
Archaeological materials are a finite resource, and efforts should be made to minimize destructive analyses. This can be achieved by using protocols combining extraction of several types of biomolecules or microparticles, which decreases the material needed for analyses while maximizing the information yield. Archaeological dental calculus is a source of several different types of biomolecules, as well as microfossils, and can tell us about the h…
Comparison of extraction methods for recovering ancient microbial DNA from paleofeces
OBJECTIVES: Paleofeces are valuable to archeologists and evolutionary biologists for their potential to yield health, dietary, and host information. As a rich source of preserved biomolecules from host-associated microorganisms, they can also provide insights into the recent evolution and changing ecology of the gut microbiome. However, there is currently no standard method for DNA extraction from paleofeces, which combine the dual challenges of …
The efficacy of whole human genome capture on ancient dental calculus and dentin
OBJECTIVES: Dental calculus is among the richest known sources of ancient DNA in the archaeological record. Although most DNA within calculus is microbial, it has been shown to contain sufficient human DNA for the targeted retrieval of whole mitochondrial genomes. Here, we explore whether calculus is also a viable substrate for whole human genome recovery using targeted enrichment techniques. MATERIALS AND METHODS: Total DNA extracted from 24 pai…
A guide to ancient protein studies
Isotopic anthropology of rural German medieval diet
This study investigates the diet of an eleventh century CE parish community located in northwestern Germany. We assessed the isotopic compositions of human (n = 24) and faunal (n = 17) bone collagen (δ13Ccol, δ15Ncol) and human structural carbonate (δ13Csc) using skeletal material recovered from the Dalheim cemetery. Traditional interpretation of the isotopic data indicates that Dalheimresidents likely relied on a C3 plant-based diet and consumed…
Bioarchaeology of the Human Microbiome
From prehistory to the present, microbes have played a significant role in the development of human society and culture—from providing essential nutrients and protection through the microbiome, to shaping populations through infectious disease, to producing fermented foods such as cheese, bread, and beer. Yet microbes are generally overlooked in studies of the human past. Recent advances in DNA technology now make it possible to investigate ancie…
Ancient DNA Investigation of a Medieval German Cemetery Confirms Long-Term Stability of CCR5-Δ32 Allele Frequencies in Central Europe
The CCR5-Δ32 mutation present in European populations is among the most prominently debated cases of recent positive selection in humans. This allele, a 32-bp deletion that renders the T-cell CCR5 receptor nonfunctional, has important epidemiological and public health significance, as homozygous carriers are resistant to several HIV strains. However, although the function of this allele in preventing HIV infection is now well described, its human…
Ancient DNA Investigation of a Medieval German Cemetery Confi rms Long-Term Stability of CCR5-Δ32 Allele Frequencies in Central Europe
The CCR5-Δ32 mutation present in European populations is among the most prominently debated cases of recent positive selection in humans. This allele, a 32-bp deletion that renders the T-cell CCR5 receptor nonfunctional, has important epidemiological and public health significance, as homozygous carriers are resistant to several HIV strains. However, although the function of this allele in preventing HIV infection is now well described, its human…
Successful enrichment and recovery of whole mitochondrial genomes from ancient human dental calculus
OBJECTIVES: Archaeological dental calculus is a rich source of host-associated biomolecules. Importantly, however, dental calculus is more accurately described as a calcified microbial biofilm than a host tissue. As such, concerns regarding destructive analysis of human remains may not apply as strongly to dental calculus, opening the possibility of obtaining human health and ancestry information from dental calculus in cases where destructive an…
Oral microbiome diversity among Cheyenne and Arapaho individuals from Oklahoma
OBJECTIVES: There is a major ascertainment bias in microbiome research, with individuals of predominately European ancestry living within metropolitan areas dominating most studies. Here we present a study of the salivary microbiome within a North American Indian community. This research is the culmination of four years of collaboration and community engagement with Cheyenne & Arapaho (C&A) tribal members from western Oklahoma. MATERIALS AND METH…
Ancient human microbiomes
Microbiome and Health in Past and Present Human Populations
Anthropological Genetics
Over the past few decades, anthropologists have increasingly used genetic approaches in their efforts to understand humans and their primate relatives.Technological and theoretical developments in recent years have enabled anthropological geneticists to expand their field of inquiry far beyond what was thought possible even a few years ago (Crawford 2000).Most importantly, the cost of collecting large genetic data sets has dropped dramatically, a…
Pathogens and host immunity in the ancient human oral cavity
Alkaline cooking and stable isotope tissue-diet spacing in swine
Maize, beans and the floral isotopic diversity of highland Oaxaca, Mexico
Disease, Demography, and Diet in Early Colonial New Spain
A mid-sixteenth-century cemetery was investigated at the colonial Mixtec site of Teposcolula Yucundaa and is shown to be related to the cocoliztli pandemic of 1544-1550. This is the earliest colonial epidemic cemetery to be identified in Mexico. Through archaeogenetic and oxygen stable isotope analysis it is demonstrated that the interred individuals were local Mixtecs, and mortuary analysis sheds light on both Christian and traditional religious…
Isotopic anthropology of rural German medieval diet
This study investigates the diet of an eleventh century CE parish community located in northwestern Germany. We assessed the isotopic compositions of human (n = 24) and faunal (n = 17) bone collagen (δ13Ccol, δ15Ncol) and human structural carbonate (δ13Csc) using skeletal material recovered from the Dalheim cemetery. Traditional interpretation of the isotopic data indicates that Dalheimresidents likely relied on a C3 plant-based diet and consumed…
Brief communication
Stressors such as fasting or poor diet quality are thought to potentially alter the nitrogen and carbon isotopic values of animal tissues. In this study, we demonstrate an inverse correlation between growth rate and multiple tissue enrichment of δ 15 N, δ 13 C, and, to a lesser degree, δ 18 O in a juvenile pig. A more complex pattern is observed with respect to tissue δD and growth rate. The observed association between growth rate and tissue iso…
Cultures of Fermentation
Recent discoveries on the importance of microbes for human biology, health, and culture, the rise of antimicrobial resistance, and developing technological advancements necessitate new dialogues about human relationships with microbes. Long perceptible only through their transformations-from epidemic disease to alcoholic beverages-it is now possible to more fully perceive the diversity of ways in which we influence and are influenced by microbes …
Ancient human microbiomes
Evidence for early dispersal of domestic sheep into Central Asia
Is Poverty in Our Genes
We present a critique of a paper written by two economists, Quamrul Ashraf and Oded Galor, which is forthcoming in the American Economic Review and which was uncritically highlighted in Science magazine. Their paper claims there is a causal effect of genetic diversity on economic success, positing that too much or too little genetic diversity constrains development. In particular, they argue that "the high degree of diversity among African popula…
Microbiome and Health in Past and Present Human Populations
Enduring Cycles
In this photo essay we elaborate on artisanal dairying practices in the European Alps and Mongolia. By comparing these geographically distant dairying practices, we view milk fermentation as a multispecies, multidomain food ecology that links bacteria, fungi, plants, animals, and humans in unbroken cycles of production and reproduction that have endured for millennia. We focus on how peasant dairy producers actively engage with microbial communit…
Successful enrichment and recovery of whole mitochondrial genomes from ancient human dental calculus
OBJECTIVES: Archaeological dental calculus is a rich source of host-associated biomolecules. Importantly, however, dental calculus is more accurately described as a calcified microbial biofilm than a host tissue. As such, concerns regarding destructive analysis of human remains may not apply as strongly to dental calculus, opening the possibility of obtaining human health and ancestry information from dental calculus in cases where destructive an…
A unified protocol for simultaneous extraction of DNA and proteins from archaeological dental calculus
Archaeological materials are a finite resource, and efforts should be made to minimize destructive analyses. This can be achieved by using protocols combining extraction of several types of biomolecules or microparticles, which decreases the material needed for analyses while maximizing the information yield. Archaeological dental calculus is a source of several different types of biomolecules, as well as microfossils, and can tell us about the h…
Comparison of extraction methods for recovering ancient microbial DNA from paleofeces
OBJECTIVES: Paleofeces are valuable to archeologists and evolutionary biologists for their potential to yield health, dietary, and host information. As a rich source of preserved biomolecules from host-associated microorganisms, they can also provide insights into the recent evolution and changing ecology of the gut microbiome. However, there is currently no standard method for DNA extraction from paleofeces, which combine the dual challenges of …
Paleobot.org
Biocultural Taphonomies and Analysis of an Emerging Terminal Classic (750–900 CE) Maya Deathway
In bioarchaeology, funerary taphonomy and preservation become part of the biocultural narrative of the dead. We evaluate the role of these factors in reconstructing the identities of those buried in an emerging deathway, the ventrally placed legs flexed (VPLF) burial position, during the Terminal Classic (750–900/1000 CE) period at the Maya polity of Lower Dover in western Belize. The term “VPLF” describes a divergent burial practice which may ha…
Your horse is a donkey! Identifying domesticated equids from Western Iberia using collagen fingerprinting
Skeletal remains of two equid species, Equus caballus (horse) and Equus asinus (donkey), have been found in archaeological contexts throughout Iberia since the Palaeolithic and Chalcolithic periods, respectively. These two species play different economic and cultural roles, and therefore it is important to be able to distinguish between the two species to better understand their relative importance in the past human societies. The most reliable m…
The efficacy of whole human genome capture on ancient dental calculus and dentin
OBJECTIVES: Dental calculus is among the richest known sources of ancient DNA in the archaeological record. Although most DNA within calculus is microbial, it has been shown to contain sufficient human DNA for the targeted retrieval of whole mitochondrial genomes. Here, we explore whether calculus is also a viable substrate for whole human genome recovery using targeted enrichment techniques. MATERIALS AND METHODS: Total DNA extracted from 24 pai…
Anthropological Genetics
Over the past few decades, anthropologists have increasingly used genetic approaches in their efforts to understand humans and their primate relatives.Technological and theoretical developments in recent years have enabled anthropological geneticists to expand their field of inquiry far beyond what was thought possible even a few years ago (Crawford 2000).Most importantly, the cost of collecting large genetic data sets has dropped dramatically, a…
Oral microbiome diversity among Cheyenne and Arapaho individuals from Oklahoma
OBJECTIVES: There is a major ascertainment bias in microbiome research, with individuals of predominately European ancestry living within metropolitan areas dominating most studies. Here we present a study of the salivary microbiome within a North American Indian community. This research is the culmination of four years of collaboration and community engagement with Cheyenne & Arapaho (C&A) tribal members from western Oklahoma. MATERIALS AND METH…
Alkaline cooking and stable isotope tissue-diet spacing in swine
Brief communication
Stressors such as fasting or poor diet quality are thought to potentially alter the nitrogen and carbon isotopic values of animal tissues. In this study, we demonstrate an inverse correlation between growth rate and multiple tissue enrichment of δ 15 N, δ 13 C, and, to a lesser degree, δ 18 O in a juvenile pig. A more complex pattern is observed with respect to tissue δD and growth rate. The observed association between growth rate and tissue iso…
Paleobot.org
Maize, beans and the floral isotopic diversity of highland Oaxaca, Mexico
Disease, Demography, and Diet in Early Colonial New Spain
A mid-sixteenth-century cemetery was investigated at the colonial Mixtec site of Teposcolula Yucundaa and is shown to be related to the cocoliztli pandemic of 1544-1550. This is the earliest colonial epidemic cemetery to be identified in Mexico. Through archaeogenetic and oxygen stable isotope analysis it is demonstrated that the interred individuals were local Mixtecs, and mortuary analysis sheds light on both Christian and traditional religious…
Is Poverty in Our Genes
We present a critique of a paper written by two economists, Quamrul Ashraf and Oded Galor, which is forthcoming in the American Economic Review and which was uncritically highlighted in Science magazine. Their paper claims there is a causal effect of genetic diversity on economic success, positing that too much or too little genetic diversity constrains development. In particular, they argue that "the high degree of diversity among African popula…
Pathogens and host immunity in the ancient human oral cavity
Ancient human microbiomes
Microbiome and Health in Past and Present Human Populations
Anthropological Genetics
Over the past few decades, anthropologists have increasingly used genetic approaches in their efforts to understand humans and their primate relatives.Technological and theoretical developments in recent years have enabled anthropological geneticists to expand their field of inquiry far beyond what was thought possible even a few years ago (Crawford 2000).Most importantly, the cost of collecting large genetic data sets has dropped dramatically, a…
Successful enrichment and recovery of whole mitochondrial genomes from ancient human dental calculus
OBJECTIVES: Archaeological dental calculus is a rich source of host-associated biomolecules. Importantly, however, dental calculus is more accurately described as a calcified microbial biofilm than a host tissue. As such, concerns regarding destructive analysis of human remains may not apply as strongly to dental calculus, opening the possibility of obtaining human health and ancestry information from dental calculus in cases where destructive an…
Oral microbiome diversity among Cheyenne and Arapaho individuals from Oklahoma
OBJECTIVES: There is a major ascertainment bias in microbiome research, with individuals of predominately European ancestry living within metropolitan areas dominating most studies. Here we present a study of the salivary microbiome within a North American Indian community. This research is the culmination of four years of collaboration and community engagement with Cheyenne & Arapaho (C&A) tribal members from western Oklahoma. MATERIALS AND METH…
Bioarchaeology of the Human Microbiome
From prehistory to the present, microbes have played a significant role in the development of human society and culture—from providing essential nutrients and protection through the microbiome, to shaping populations through infectious disease, to producing fermented foods such as cheese, bread, and beer. Yet microbes are generally overlooked in studies of the human past. Recent advances in DNA technology now make it possible to investigate ancie…
Ancient DNA Investigation of a Medieval German Cemetery Confirms Long-Term Stability of CCR5-Δ32 Allele Frequencies in Central Europe
The CCR5-Δ32 mutation present in European populations is among the most prominently debated cases of recent positive selection in humans. This allele, a 32-bp deletion that renders the T-cell CCR5 receptor nonfunctional, has important epidemiological and public health significance, as homozygous carriers are resistant to several HIV strains. However, although the function of this allele in preventing HIV infection is now well described, its human…
Ancient DNA Investigation of a Medieval German Cemetery Confi rms Long-Term Stability of CCR5-Δ32 Allele Frequencies in Central Europe
The CCR5-Δ32 mutation present in European populations is among the most prominently debated cases of recent positive selection in humans. This allele, a 32-bp deletion that renders the T-cell CCR5 receptor nonfunctional, has important epidemiological and public health significance, as homozygous carriers are resistant to several HIV strains. However, although the function of this allele in preventing HIV infection is now well described, its human…
A guide to ancient protein studies
Isotopic anthropology of rural German medieval diet
This study investigates the diet of an eleventh century CE parish community located in northwestern Germany. We assessed the isotopic compositions of human (n = 24) and faunal (n = 17) bone collagen (δ13Ccol, δ15Ncol) and human structural carbonate (δ13Csc) using skeletal material recovered from the Dalheim cemetery. Traditional interpretation of the isotopic data indicates that Dalheimresidents likely relied on a C3 plant-based diet and consumed…
The efficacy of whole human genome capture on ancient dental calculus and dentin
OBJECTIVES: Dental calculus is among the richest known sources of ancient DNA in the archaeological record. Although most DNA within calculus is microbial, it has been shown to contain sufficient human DNA for the targeted retrieval of whole mitochondrial genomes. Here, we explore whether calculus is also a viable substrate for whole human genome recovery using targeted enrichment techniques. MATERIALS AND METHODS: Total DNA extracted from 24 pai…
A unified protocol for simultaneous extraction of DNA and proteins from archaeological dental calculus
Archaeological materials are a finite resource, and efforts should be made to minimize destructive analyses. This can be achieved by using protocols combining extraction of several types of biomolecules or microparticles, which decreases the material needed for analyses while maximizing the information yield. Archaeological dental calculus is a source of several different types of biomolecules, as well as microfossils, and can tell us about the h…
Comparison of extraction methods for recovering ancient microbial DNA from paleofeces
OBJECTIVES: Paleofeces are valuable to archeologists and evolutionary biologists for their potential to yield health, dietary, and host information. As a rich source of preserved biomolecules from host-associated microorganisms, they can also provide insights into the recent evolution and changing ecology of the gut microbiome. However, there is currently no standard method for DNA extraction from paleofeces, which combine the dual challenges of …
Evidence for early dispersal of domestic sheep into Central Asia
Enduring Cycles
In this photo essay we elaborate on artisanal dairying practices in the European Alps and Mongolia. By comparing these geographically distant dairying practices, we view milk fermentation as a multispecies, multidomain food ecology that links bacteria, fungi, plants, animals, and humans in unbroken cycles of production and reproduction that have endured for millennia. We focus on how peasant dairy producers actively engage with microbial communit…
Cultures of Fermentation
Recent discoveries on the importance of microbes for human biology, health, and culture, the rise of antimicrobial resistance, and developing technological advancements necessitate new dialogues about human relationships with microbes. Long perceptible only through their transformations-from epidemic disease to alcoholic beverages-it is now possible to more fully perceive the diversity of ways in which we influence and are influenced by microbes …
Your horse is a donkey! Identifying domesticated equids from Western Iberia using collagen fingerprinting
Skeletal remains of two equid species, Equus caballus (horse) and Equus asinus (donkey), have been found in archaeological contexts throughout Iberia since the Palaeolithic and Chalcolithic periods, respectively. These two species play different economic and cultural roles, and therefore it is important to be able to distinguish between the two species to better understand their relative importance in the past human societies. The most reliable m…
An Archaeology of Microbes
Humans have a deep and complex relationship with microbes. Beyond disease, microbes also profoundly shape human health and behavior through their activity in the microbiome and their diverse roles in food and cuisine. And yet we know very little about the origin, evolution, or ecology of the trillions of microorganisms that call us home. Recent advances in genomic and proteomic technologies are opening up dramatic new opportunities in the field o…
Biology (20 obras) · Archaeology and ancient environmental studies (14 obras) · Geography (12 obras) · Archaeology (11 obras) · Ecology (11 obras) · Ancient DNA (10 obras) · Medicine (8 obras) · Computer Science (7 obras) · Forensic Anthropology and Bioarchaeology Studies (7 obras) · Genetics (7 obras)