The Ethics of End-of-Trial Obligations in a Pediatric Malaria Vaccine Trial
The Perspectives of Stakeholders From Ghana and Tanzania
Bibliographic Data
| ID | 12807125 |
|---|---|
| Authors | Claire Leonie Ward (0000-0002-4813-0133, University of Basel, corresponding author), David Shaw (0000-0001-8180-6927, University of Basel), Evelyn Anane‐Sarpong (0000-0002-9960-9080, University of Basel), Osman Sankoh (0000-0003-4405-9808, Indepth Network), Marcel Tanner (0000-0002-1205-6971, University of Basel), Bernice S Elger (0000-0002-4249-7399, University of Basel) |
| Year | 2018 |
| Volume | 13 |
| Issue | 3 |
| Pages | 258-269 |
| Publication date | 2018-05-13 |
| Peer Reviewed | Yes |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | Journal of Empirical Research on Human Research Ethics (JOURNAL) |
| Journal identifiers | ISSN: 1556-2646 • E-ISSN: 1556-2654 |
| Publisher | SAGE Publishing (PUBLISHER • US) |
| DOI | 10.1177/1556264618771809 |
| PMID | 29756531 |
| OpenAlex | W2804817005 |
| Language | EN |
| Citations received | 1 |
| References cited | 31 |
This study explores stakeholder experiences and perspectives on end-of-trial obligations at the close of a phase II/III Pediatric Malaria Vaccine Trial (PMVT) [GSK/PATH-MVI RTS, S) (NCT00866619]. We conducted 52 key informant interviews with major stakeholders of an international multicentre PMVT in Ghana and Tanzania. The responses fell into four main themes: (a) Communicating End-of-Trial, (b) Maintaining Health Care Services, (c) Dissemination of Results, and (d) Post-Trial Access. Interviewee responses shared important practical experiences and insights that complement current thinking in the literature on research ethics guidance: (a) accompany end-of-trial communication with information on personal and family health care responsibilities, (b) establish public health indicators to measure the impact of research on a health care system
Alternative medicine · Bioethics · Clinical trial · Ethics committee · Informed consent · Malaria · Malaria vaccine · Plasmodium falciparum · Political science · Psychiatry · Research ethics · Socioeconomics · Sociology · Tanzania · Ethics in Clinical Research · Law · Medicine · Pharmaceutical studies and practices · Public Administration · Vaccine Coverage and Hesitancy · Immunology · Internal Medicine
International Ethical Guidelines for Health-related Research involving Humans
Defining Health Research for Development
Engaging Diverse Social and Cultural Worlds
Evolving Friendships and Shifting Ethical Dilemmas
Mind the gap
Benefit Sharing in a Global Context
Women in Developing Countries and Benefit Sharing
The Ethics of Health Care Delivery in a Pediatric Malaria Vaccine Trial
| Unique citing works | 1 |
|---|---|
| Citations per year | 0,13 |
| Citation span | 2018 - 2018 (1) |
| Citation velocity | historical |
| Highly cited | No |
| Citation types | Neutral: 1 |