Catha edulis and Datura stramonium mitigate oxidative stress, mitochondrial dysfunction, and cell death in an SH-SY5Y model of Parkinson's disease
Bibliographic Data
| ID | 14727836 |
|---|---|
| Authors | T Mogale (University of Pretoria), A D de Beer (0000-0002-5755-5969, University of Pretoria), W J Rudolph (University of Pretoria), V Steenkamp (0000-0003-3575-0410, University of Pretoria) |
| Year | 2026 |
| Volume | 360 |
| Pages | 121223 |
| Publication date | 2026-04-01 |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | Journal of Ethnopharmacology (JOURNAL) |
| Journal identifiers | ISSN: 0378-8741 • E-ISSN: 1872-7573 |
| Publisher | Elsevier BV (PUBLISHER) |
| DOI | 10.1016/j.jep.2026.121223 |
| PMID | 41548622 |
| OpenAlex | W7124421765 |
| Language | EN |
| Citations received | 1 |
| References cited | 89 |
Both plant extracts preserved cell viability, reduced ROS levels, and maintained mitochondrial integrity, highlighting their potential as therapeutic agents for PD
Cell · Datura stramonium · Disease · Mitochondrion · Oxidative damage · Oxidative phosphorylation · Oxidative stress · Programmed cell death · Neurotransmitter Receptor Influence on Behavior · Parkinson's Disease Mechanisms and Treatments · Traditional and Medicinal Uses of Annonaceae
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| Citations per year | 1 |
|---|---|
| Citation span | 2026 - 2026 (1) |
| Highly cited | No |