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Exploring the therapeutic potential of Xiangsha Liujunzi Wan in Crohn's disease

From network pharmacology approach to experimental validation

Bibliographic Data

ID14743153
AuthorsLinlin Zheng (0000-0002-8902-1056, China Medical University), Ziyun Wei (0000-0001-8913-1389, China Medical University), Xiao Ni (0000-0002-8159-9275, China Medical University), Jianing Shang (China Medical University), Fu Liu (0000-0003-1461-9608, China Medical University), Yuxuan Peng (0000-0001-7874-1368, China Medical University), Jieyu Liu (0000-0001-8330-5376, China Medical University, corresponding author), Yunwei Li (0000-0002-5410-4505, First Hospital of China Medical University, corresponding author)
Year2025
Volume337
IssuePt 2
Pages118863
Publication date2025-01-01
Open AccessYes
TypeARTICLE
VenueJournal of Ethnopharmacology (JOURNAL)
Journal identifiersISSN: 0378-8741 • E-ISSN: 1872-7573
PublisherElsevier BV (PUBLISHER)
DOI10.1016/j.jep.2024.118863
PMID39343107
OpenAlexW4402913712
LanguageEN
Citations received1
References cited61

LJZW has the characteristics of multi-component, multi-target, and multi-pathway treatment, which helps to improve the treatment of CD, protect the intestinal barrier, and exert the effect of anti-inflammatory therapy by inhibiting PI3K-AKT and MAPK signaling pathways

Crohn's disease · Disease · Traditional medicine · Medicine · Natural product bioactivities and synthesis · Pharmacological Effects of Natural Compounds · Phytochemistry and Bioactive Compounds · Internal Medicine · Pharmacology

  • Shen-Ling-Bai-Zhu-San alleviates Crohn's disease-like colitis by modulating fatty acid degradation via the peroxisome proliferation-activated receptor pathway

    Open Access•Linlin Zheng, Anqi Cui et al.•Journal of Ethnopharmacology•2025

  • The STRING database in 2021

    Open Access•Damian Szklarczyk, Annika L Gable et al.•Nucleic Acids Research•2021

Citations per year1
Citation span2025 - 2025 (1)
Highly citedNo

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