N-Propylthiouracil sensitivity and obesity status among ethnically diverse children

Bibliographic Data

ID15096280
AuthorsJanice Baranowski (0000-0003-0717-0056, Children's Nutrition Research Center at Baylor College of Medicine, corresponding author), Janice C Baranowski, Tom Baranowski (0000-0002-0653-2222, Baylor College of Medicine), Alicia Beltran (0000-0003-3888-7500, Children's Nutrition Research Center at Baylor College of Medicine), Kathy Watson (Children's Nutrition Research Center at Baylor College of Medicine), Kathy B Watson, Russell Jago (0000-0002-3394-0176, Children's Nutrition Research Center at Baylor College of Medicine), Margaret Callie (Children's Nutrition Research Center at Baylor College of Medicine), Mariam Missaghian (International Research Associates (United States)), Beverly J Tepper (0000-0002-5033-6632, Rutgers, the State University of New Jersey)
Year2010
Volume13
Issue10
Pages1587-1592
Publication date2010-10-01
Peer ReviewedYes
Open AccessYes
TypeARTICLE
VenuePublic Health Nutrition (JOURNAL)
Journal identifiersISSN: 1368-9800 • E-ISSN: 1475-2727
PublisherCambridge University Press (CUP) (PUBLISHER)
DOI10.1017/s1368980009993004
PMID20025833
OpenAlexW2047849908
LanguageEN
Citations received4
References cited17

Objective To examine the relationship of 6-n-propylthiouracil (PROP) sensitivity to BMI while statistically controlling for demographic characteristics in two age groups of children: 9–10 years and 17–18 years ( n 1551). Design Cross-sectional design with a multi-ethnic (White, African-American, Hispanic, Other) sample of 813 children aged 9–10 years and 738 children aged 17–18 years. Children were recruited from local elementary and high schools with at least 30 % minority ethnic enrolment. Children’s height, weight and waist circumference were measured along with their PROP taster status. PROP was measured using two paper discs, one impregnated with NaCl (1·0 mol/l) and the other with PROP solution (0·50 mmol/l). Results A significant PROP sensitivity by socio-economic status (SES) interaction term ( P = 0·010) was detected wherein supertasters had the largest BMI percentile and Z -score, but only among the group with highest SES. Conclusions The results suggest that other factors overwhelmed the influence of PROP sensitivity on adiposity in lower-SES groups. The percentage of variance accounted for by the interaction term was about 1 %. Thus, PROP supertasters had the largest BMI percentile and Z -score, but only among the highest-SES group

Body mass index · Circumference · Ethnic group · Obesity · Overweight · Percentile · Statistics · Waist · Biochemical Analysis and Sensing Techniques · Demography · Mathematics · Medicine · Nutrition, Health and Food Behavior · Obesity, Physical Activity, Diet · Internal Medicine · Pediatrics

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