Folate and folic acid in the periconceptional period
Recommendations from official health organizations in thirty-six countries worldwide and WHO
Bibliographic Data
| ID | 15097007 |
|---|---|
| Authors | Sandra Gomes (0000-0002-7703-6488), Sandra Cristina da Silva Gomes (0000-0002-7093-7371, Universidade do Porto), Carla Lopes (0000-0003-1524-852X, Universidade do Porto), Elisabete Pinto (0000-0001-9028-8009, Universidade Católica Portuguesa, corresponding author) |
| Year | 2016 |
| Volume | 19 |
| Issue | 1 |
| Pages | 176-189 |
| Publication date | 2016-01-01 |
| Peer Reviewed | Yes |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | Public Health Nutrition (JOURNAL) |
| Journal identifiers | ISSN: 1368-9800 • E-ISSN: 1475-2727 |
| Publisher | Cambridge University Press (CUP) (PUBLISHER) |
| DOI | 10.1017/s1368980015000555 |
| PMID | 25877429 |
| OpenAlex | W2143135457 |
| Language | EN |
| Citations received | 9 |
| References cited | 40 |
Objective To summarize the recommendations on folate intake and folic acid supplementation and fortification in the periconceptional period, aimed at prevention of neural tube defects (NTD), provided by official health organizations in different countries worldwide and WHO. Design Information on recommendations for folate and folic acid intake in the periconceptional period was gathered from the websites of official national health organizations of several countries worldwide and from the WHO website. Setting WHO, selected developed countries and emerging economies, totalling thirty-six countries worldwide (some European, BRICS, G8, Asian Tiger/Asian Dragon and Australia). Results Recommendations differ between countries, although the majority (69·4 %) recommend a healthy diet plus a folic acid supplement of 400 μg/d from preconception (4–12 weeks) until the end of the first trimester of pregnancy (8–12 weeks). The same recommendation is issued by the WHO. Dosages for women at high risk of NTD are up to 4–5 mg/d (for 41·7 % of studied countries). The recommended intake for folate is in the range of 300–400 μg/d for women of childbearing age and 500–600 μg/d for pregnant women in different countries and WHO. Five countries emphasize the importance of a healthy diet rendering supplementation needless. By contrast, five others advise a healthy diet and supplementation plus mandatory fortification. Only one mentions the importance of ensuring an adequate folate status and refers to checking with a health-care provider on the need for supplements. Conclusions Different recommendations regarding folate and folic acid, seeking NTD prevention, are available worldwide; however, most countries and WHO focus on a healthy diet and folic acid supplementation of 400 μg/d periconceptionally
Developed country · Developing country · Economic growth · Environmental health · folic acid · Food fortification · Fortification · Geography · Population · Pregnancy · Folate and B Vitamins Research · Medicine · Pregnancy and Medication Impact · Pregnancy and preeclampsia studies · Pediatrics
Artificial intelligence for health message generation
Maternal Folic Acid Supplementation, Dietary Folate Intake, and Low Birth Weight
The Associations between the Duration of Folic Acid Supplementation, Gestational Diabetes Mellitus, and Adverse Birth Outcomes based on a Birth Cohort
An evaluation of adherence to folic acid supplementation in pregnant women during early gestation for the prevention of neural tube defects
Folic acid deficiency declined substantially after introduction of the mandatory fortification programme in Queensland, Australia
The association between serum folate and gestational diabetes mellitus
Effects of folic acid food fortification scenarios on the folate intake of a multi-ethnic pregnant population
Determinants of folic acid supplement use outside national recommendations for pregnant women
Awareness, use and information sources of folic acid supplementation to prevent neural tube defects in pregnant Japanese women
Prevention of the First Occurrence of Neural-Tube Defects by Periconceptional Vitamin Supplementation
Dietary intake and nutritional adequacy prior to conception and during pregnancy
Infant mortality and congenital anomalies from 1950 to 1994
Unintended Pregnancy
Adequacy of prenatal care as a major determinant of folic acid, iron, and vitamin intake during pregnancy
| Unique citing works | 9 |
|---|---|
| Citations per year | 1,13 |
| Citation span | 2018 - 2023 (6) |
| Citation velocity | historical |
| Highly cited | No |
| Citation types | Neutral: 9 |