These Girls Have a Chance to be the Future Generation of HIV Negative”
Experiences of Implementing a PrEP Programme for Adolescent Girls and Young Women in South Africa
Bibliographic Data
| ID | 15334236 |
|---|---|
| Authors | Zoe Duby (0000-0001-7615-8152, South African Medical Research Council, corresponding author), Brittany Bunce (0000-0003-4872-4238, University of Sheffield), Chantal Fowler (University of Cape Town), Kim Jonas (0000-0002-4469-6674, South African Medical Research Council), Kate Bergh (0000-0001-5471-5819, South African Medical Research Council), Darshini Govindasamy (0000-0001-5984-3588, South African Medical Research Council), Devin Govindasamy (0000-0002-0665-0595), Colleen Wagner (0000-0002-6704-5014), Catherine Mathews (0000-0001-5368-1127, South African Medical Research Council) |
| Year | 2022 |
| Volume | 27 |
| Issue | 1 |
| Pages | 134-149 |
| Publication date | 2022-07-06 |
| Peer Reviewed | Yes |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | AIDS and Behavior (JOURNAL) |
| Journal identifiers | ISSN: 1090-7165 • E-ISSN: 1573-3254 |
| Publisher | Springer Science+Business Media (PUBLISHER • DE) |
| DOI | 10.1007/s10461-022-03750-1 |
| PMID | 35793053 |
| OpenAlex | W4283837320 |
| Language | EN |
| Citations received | 18 |
| References cited | 44 |
Daily oral pre-exposure prophylaxis (PrEP) is highly efficacious for HIV prevention. Adolescent girls and young women (AGYW) have been prioritised for PrEP delivery in South Africa. A combination HIV prevention intervention providing integrated biomedical, behavioural and structural interventions for AGYW aged 15-24 in twelve districts in South Africa characterised by high HIV prevalence, was implemented 2019-2022. We conducted qualitative interviews to explore PrEP implementation experiences with 38 individuals involved in the implementation of the combination HIV prevention programme, including programme managers and project coordinators, health care providers / nurses, social workers, counsellors, peer group trainers and outreach workers. Narratives included various challenges associated with PrEP uptake, adherence and acceptability experienced by implementers. Barriers to PrEP acceptability included AGYW fears of side effects and preference for injectable versus daily oral PrEP; resistance towards PrEP from AGYW, communities and parents due to a lack of accurate information; PrEP stigma linked to associations with antiretrovirals and assumptions of promiscuity; and issues pertaining to parental consent. Additionally, implementers faced logistical challenges related to procurement, stockouts, and supply of PrEP. Findings highlighted the critical role of parental and community acceptability of PrEP for successful implementation. Overall, PrEP was perceived by implementers as a valuable HIV prevention tool. In order to ensure the accessibility of PrEP for AGYW in South Africa, efforts to reduce stigma and foster social support for PrEP use, campaigns to raise awareness, ensure positive framing of PrEP, and build community acceptability of PrEP, are needed
Family medicine · Health psychology · Human immunodeficiency virus (HIV · Intervention (counseling · Men who have sex with men · Outreach · Pre-exposure prophylaxis · Psychiatry · Psychological intervention · Public health · Qualitative research · Stigma (botany · Adolescent Sexual and Reproductive Health · HIV, Drug Use, Sexual Risk · HIV/AIDS Research and Interventions · Medicine · Nursing
A Systematic Review of Barriers and Facilitators to the Uptake and Adherence of Injectable PrEP Among Adolescent Girls and Young Women in Sub-Saharan Africa
Exploring Adolescent Girls’ and Young Women’s Perceptions of HIV Prevention Pre-exposure Prophylaxis Use
Balancing risk and reward
A qualitative study of peer education experiences and oral pre-exposure prophylaxis use among adolescent girls and young women at high risk of HIV acquisition in Kampala, Uganda
The experience of healthcare workers to HIV pre-exposure prophylaxis (PrEP) implementation in low- and middle-income countries
Adolescent girls and young women as a critical population for HIV epidemic control in sub-Saharan Africa
“I will take PrEP because that’s what will help me not to get infected with HIV”
“If I wasn’t a pastor, I would be telling them about condoms, contraceptives and PrEP”—conflicts, dilemmas and credibility
Revitalizing folklore for HIV/Aids messaging in South Africa
Contraception and PrEP knowledge, attitudes, and practices among adolescent girls and young women in Nampula, Mozambique
Peer providers delivering health and wellbeing services for adolescents and youth – a scoping review of implementation experience and impact from Eastern and Southern Africa
What drives adolescent girls and young women's decisions to persist on PrEP? Results of a comparative qualitative study from a DREAMS program in western Kenya
Awareness and uptake of oral pre-exposure prophylaxis among adolescent and young key populations in Nigeria
Adult Stakeholders’ Perspectives on the Content, Design, and Dissemination of Sexual and Gender Minority Adolescent-Centered PrEP Campaigns
Empowering women at risk
Applying the HIV Prevention Cascade to an Evaluation of a Large-Scale Combination HIV Prevention Programme for Adolescent Girls and Young Women in South Africa
Motivations for Starting and Stopping PrEP
Integrating PrEP and Sexual Reproductive Health Services for Adolescent Girls and Young Women in South Africa
Acceptability of healthcare interventions
HIV pre‐exposure prophylaxis for adolescent girls and young women in Africa
Stigma and Shame Experiences by MSM Who Take PrEP for HIV Prevention
Understanding, Contextualizing, and Addressing PrEP Stigma to Enhance PrEP Implementation
Memoing in qualitative research
Covid-19 Related Medical Mistrust, Health Impacts, and Potential Vaccine Hesitancy Among Black Americans Living With HIV
The influence of HIV‐related stigma on PrEP disclosure and adherence among adolescent girls and young women in HPTN 082
Tailoring Communication to Increase the Promotion of Oral PrEP
“Condoms Are Boring”
Facilitators and barriers to HIV pre-exposure prophylaxis (PrEP) uptake through a community-based intervention strategy among adolescent girls and young women in Seme Sub-County, Kisumu, Kenya
Motivated Reasoning and HIV Risk? Views on Relationships, Trust, and Risk from Young Women in Cape Town, South Africa, and Implications for Oral PrEP
Delivering PrEP to Young Women in a Low-Income Setting in South Africa
Medical Mistrust and the PrEP Cascade Among Latino Sexual Minority Men
Experiences of Anticipated and Enacted Pre-exposure Prophylaxis (PrEP) Stigma Among Latino MSM in Los Angeles
From Survival to Glamour
Qualitative Assessment of Barriers and Facilitators of PrEP Use Before and After Rollout of a PrEP Program for Priority Populations in South-central Uganda
Maternal PrEP Use in HIV-Uninfected Pregnant Women in South Africa
The PrEP Journey
Sexual scripting of heterosexual penile-anal intercourse amongst participants in an HIV prevention trial in South Africa, Uganda and Zimbabwe
Religious leaders’ role in pregnant and breastfeeding women’s decision making and willingness to use biomedical HIV prevention strategies
Adolescent-Centered HIV Prevention
| Unique citing works | 18 |
|---|---|
| Citations per year | 6 |
| Citation span | 2023 - 2026 (4) |
| Citation velocity | current |
| Highly cited | No |
| Citation types | Neutral: 16 |