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“I will take PrEP because that’s what will help me not to get infected with HIV”

Barriers to and facilitators of pre-exposure prophylaxis and condom use among adolescent girls and young women enrolled in a school-based HIV prevention program in South Africa

Bibliographic Data

ID22069154
AuthorsKate Bergh (0000-0001-5471-5819, South African Medical Research Council, corresponding author), Kim Jonas (0000-0002-4469-6674, South African Medical Research Council), Elona Toska (0000-0002-3800-3173, University of Cape Town), Fareed Abdullah (0000-0002-1118-9430, South African Medical Research Council), Nomtopi Blom (South African Medical Research Council), Catherine Mathews (0000-0001-5368-1127, South African Medical Research Council), Ngkatiseng Mthanti (South African Medical Research Council), Nevilene Slingers (0000-0002-1670-1755, South African Medical Research Council), Nathanael van Blydenstein (Network of AIDS Researchers of Eastern and Southern Africa), Zoe Duby (0000-0001-7615-8152, South African Medical Research Council)
Year2025
Volume13
Pages1616261-1616261
Publication date2025-11-20
Peer ReviewedYes
Open AccessYes
TypeARTICLE
VenueFrontiers in Public Health (JOURNAL)
Journal identifiersISSN: 2296-2565 • E-ISSN: 2296-2565
PublisherFrontiers Media SA (PUBLISHER • CH)
DOI10.3389/fpubh.2025.1616261
PMID41368666
OpenAlexW4416387305
LanguageEN
Citations received3
References cited40

Introduction: The Imagine programme is a school-based HIV prevention program offering preexposure prophylaxis (PrEP), condoms and other social and structural interventions to adolescent girls and young women (AGYW) in South Africa. PrEP uptake and adherence together with the provision of condoms has not been extensively studied in the school context. We explored the barriers to and facilitators of PrEP and condom usage among Imagine programme beneficiaries using the HIV prevention cascade framework. Methods: Sixteen AGYW aged 16-20 years who had never taken PrEP, were on PrEP or had stopped PrEP were interviewed between November 2023 and March 2024. Interviews were audio-recorded, and transcripts were deductively coded according to the HIV prevention cascade steps: (1) Knowledge, (2) Motivation, (3) Access and (4) Effective use. Results: HIV and pregnancy risk awareness was high. For condom use, the risk of HIV transmission and pregnancy was outweighed by fear of sexual or physical violence from male partners and a desire to maintain relationships, as asking to use condoms demonstrated a lack of trust. High levels of PrEP knowledge motivated participants to use PrEP, especially if their partner refused to use condoms. Fear of side effects and daily pill taking were barriers to PrEP uptake. PrEP and condom services in school were highly acceptable, while anticipated stigma remained a challenge at the community clinic. Discussion: Barriers to condom use persist in South Africa, but positive attitudes toward PrEP described in this study suggest that opinions about PrEP are still forming and can be strongly influenced by youth-friendly HIV programming in schools

Condom · Family planning · Female condom · Population · Pre-exposure prophylaxis · Public health · Adolescent Sexual and Reproductive Health · HIV/AIDS Research and Interventions · Sex work and related issues

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Unique citing works3
Citations per year3
Citation span2025 - 2026 (2)
Citation velocitycurrent
Highly citedNo
Citation typesNeutral: 3

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