Non-alcoholic Fatty Liver Disease and Depression
Evidence for Genotype × Environment Interaction in Mexican Americans
Dados Bibliográficos
| ID | 15524328 |
|---|---|
| Autores | Eron G Manusov (0000-0002-6052-1823, The University of Texas Rio Grande Valley, autor correspondente), Vincent P Diego (0000-0002-0007-2085, The University of Texas Rio Grande Valley), Khalid H Sheikh (0000-0002-1477-6358, The University of Texas Rio Grande Valley), Khalid Sheikh, Sandra Laston (The University of Texas Rio Grande Valley), John Blangero (0000-0001-6250-5723, The University of Texas Rio Grande Valley), Sarah Williams-Blangero, Sarah Williams‐blangero (0000-0002-4456-222X, The University of Texas Rio Grande Valley) |
| Ano | 2022 |
| Volume | 13 |
| Páginas | 936052-936052 |
| Data de publicação | 2022-07-01 |
| Peer Reviewed | Sim |
| Open Access | Sim |
| Tipo | ARTICLE |
| Periódico | Frontiers in Psychiatry (JOURNAL) |
| Identificadores do periódico | ISSN: 1664-0640 • E-ISSN: 1664-0640 |
| Editora | Frontiers Media (PUBLISHER • CH) |
| DOI | 10.3389/fpsyt.2022.936052 |
| PMID | 35845438 |
| OpenAlex | W4283779487 |
| Idioma | EN |
| Citações recebidas | 1 |
| Referências citadas | 61 |
This study examines the impact of G × E interaction effects on non-alcoholic fatty liver disease (NAFLD) among Mexican Americans in the Rio Grande Valley (RGV) of South Texas. We examined potential G × E interaction using variance components models and likelihood-based statistical inference in the phenotypic expression of NAFLD, including hepatic steatosis and hepatic fibrosis (identified using vibration controlled transient elastography and controlled attenuation parameter measured by the FibroScan Device). We screened for depression using the Beck Depression Inventory-II (BDI-II). We identified significant G × E interactions for hepatic fibrosis × BDI-II. These findings provide evidence that genetic factors interact with depression to influence the expression of hepatic fibrosis
Alcoholic liver disease · Anxiety · Beck Depression Inventory · Biology · Cirrhosis · Depression (economics · Disease · Fatty liver · Fibrosis · Gene · Genotype · Liver fibrosis · Psychiatry · Steatosis · Transient elastography · Clinical Psychology · Hepatitis C virus research · Liver Disease Diagnosis and Treatment · Liver Diseases and Immunity · Medicine · Psychology · Gastroenterology · Genetics · Internal Medicine
| Obras citantes distintas | 1 |
|---|---|
| Citações por ano | 0,5 |
| Intervalo de citações | 2024 - 2024 (1) |
| Velocidade de citação | recent |
| Altamente citado | Não |
| Tipos de citação | Neutras: 1 |