Exploring brain glutathione and peripheral blood markers in posttraumatic stress disorder

A combined [1H]MRS and peripheral blood study

Bibliographic Data

ID15529934
AuthorsSarah E Watling (Centre for Addiction and Mental Health), Shawn G Rhind (0000-0003-2300-0620, University of Toronto), Jerry J Warsh (University of Toronto), Jerry Warsh, Duncan Green (University of Toronto), Tina McCluskey (0000-0002-6795-4808, Centre for Addiction and Mental Health), Junchao Tong (0000-0001-9299-0045, Centre for Addiction and Mental Health), Peter Truong (Centre for Addiction and Mental Health), Sofia Chavez (0000-0002-6532-911X, Centre for Addiction and Mental Health), Julie Richardson (0000-0003-4909-395X, McMaster University), J Don Richardson (0000-0002-2927-6735), Stephen J Kish (0000-0003-0237-1756, University of Toronto), Isabelle Boileau (0000-0002-9901-1484, University of Toronto, corresponding author)
Year2023
Volume14
Pages1195012-1195012
Publication date2023-06-02
Open AccessYes
TypeARTICLE
VenueFrontiers in Psychiatry (JOURNAL)
Journal identifiersISSN: 1664-0640 • E-ISSN: 1664-0640
PublisherFrontiers Media (PUBLISHER • CH)
DOI10.3389/fpsyt.2023.1195012
PMID37333909
OpenAlexW4379232822
LanguageEN
References cited80

We do not report altered GSH concentrations in the ACC or DLPFC in PTSD, however, systemic MMPs and MPO might be implicated in central processes and progression of PTSD. Future research should investigate these relationships in larger sample sizes

Anterior cingulate cortex · Cognition · Dorsolateral prefrontal cortex · Glutathione · Inflammation · Myeloperoxidase · Oxidative stress · Peripheral · Posttraumatic stress · Prefrontal cortex · Psychiatry · Chemistry · Medicine · Psychology · Stress Responses and Cortisol · Traumatic Brain Injury and Neurovascular Disturbances · Tryptophan and brain disorders · Biochemistry · Endocrinology · Internal Medicine

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