Age at first introduction to complementary foods is associated with sociodemographic factors in children with increased genetic risk of developing type 1 diabetes

Bibliographic Data

ID15535823
AuthorsCarin Andrén Aronsson (0000-0003-0256-9367, Lund University, corresponding author), Ulla Uusitalo (0000-0001-9132-7727, University of South Florida), Kendra Vehik (0000-0001-6243-6772, University of South Florida), Jimin Yang (0000-0002-9829-6916, University of South Florida), Katherine Silvis (0000-0001-7283-0570, Augusta University), Sandra Hummel (0000-0001-5272-9811, Helmholtz Zentrum München), Suvi M Virtanen (Nutrition Unit National Institute for Health and Welfare Helsinki Finland), Suvi Μ Virtanen (0000-0001-8928-0878, Tampere University Hospital), Jill M Norris (0000-0002-3502-7671, Colorado School of Public Health), TEDDY Study Group
Year2013
Volume11
Issue4
Pages803-814
Publication date2013-09-13
Peer ReviewedYes
Open AccessYes
TypeARTICLE
VenueMaternal and Child Nutrition (JOURNAL)
Journal identifiersISSN: 1740-8695 • E-ISSN: 1740-8709
PublisherWiley (PUBLISHER • GB)
DOI10.1111/mcn.12084
PMID24034553
PMCIDPMC4122645
OpenAlexW2136603681
LanguageEN
Citations received6
References cited27

Infant's age at introduction to certain complementary foods (CF) has in previous studies been associated with islet autoimmunity, which is an early marker for type 1 diabetes (T1D). Various maternal sociodemographic factors have been found to be associated with early introduction to CF. The aims of this study were to describe early infant feeding and identify sociodemographic factors associated with early introduction to CF in a multinational cohort of infants with an increased genetic risk for T1D. The Environmental Determinants of Diabetes in the Young study is a prospective longitudinal birth cohort study. Infants (N = 6404) screened for T1D high risk human leucocyte antigen-DQ genotypes (DR3/4, DR4/4, DR4/8, DR3/3, DR4/4, DR4/1, DR4/13, DR4/9 and DR3/9) were followed for 2 years at six clinical research centres: three in the United States (Colorado, Georgia/Florida, Washington) and three in Europe (Sweden, Finland, Germany). Age at first introduction to any food was reported at clinical visits every third month from the age of 3 months. Maternal sociodemographic data were self-reported through questionnaires. Age at first introduction to CF was primarily associated with country of residence. Root vegetables and fruits were usually the first CF introduced in Finland and Sweden and cereals were usually the first CF introduced in the United States. Between 15% and 20% of the infants were introduced to solid foods before the age of 4 months. Young maternal age (<25 years), low educational level (<12 years) and smoking during pregnancy were significant predictors of early introduction to CF in this cohort. Infants with a relative with T1D were more likely to be introduced to CF later

Cohort · Cohort study · Diabetes mellitus · Environmental health · Population · Prospective cohort study · Residence · Type 1 diabetes · Demography · Diabetes and associated disorders · Diet, Metabolism, and Disease · Medicine · Obesity, Physical Activity, Diet · Internal Medicine · Pediatrics

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