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Perinatal Characteristics and the Sensitization to Cow Milk, Egg Whites and Wheat in Children up to 3 Years of Age

Bibliographic Data

ID15716281
AuthorsHsin-Yu Chang (0000-0001-5577-2356, Chang Gung University), Zon‐Min Lee (0000-0003-3470-2468, Tajen University), Zon-Min Lee (Department of Pharmacy, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung 833, Taiwan), Ling‐Sai Chang (0000-0002-3591-1563, Chang Gung University), Ling-Sai Chang (Department of Pediatrics, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung 833, Taiwan), Wei-Ling Feng (Kaohsiung Chang Gung Memorial Hospital), Yao‐Hsu Yang (0000-0002-8080-0504, Chang Gung University), Mei‐Chen Ou‐Yang (0000-0002-6369-4738, Chang Gung University, corresponding author), Mei-Chen Ou-Yang (Department of Pediatrics, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung 833, Taiwan)
Year2023
Volume10
Issue5
Pages860-860
Publication date2023-05-11
Open AccessYes
TypeARTICLE
VenueChildren (JOURNAL)
Journal identifiersISSN: 2227-9067 • E-ISSN: 2227-9067
PublisherMultidisciplinary Digital Publishing Institute (PUBLISHER • CH)
DOI10.3390/children10050860
PMID37238408
OpenAlexW4376255088
LanguageEN
Citations received1
References cited53

Food sensitization in early life identifies children at risk of developing allergic diseases. We investigated the sensitization to cow milk (CM), egg whites, and wheat. Newborns and infants under 3 years of age with available specific immunoglobulin E (sIgE) data were identified. A retrospective survey was conducted using data from the Chang Gung Research Database. Perinatal characteristics, such as singleton or multiples in a single pregnancy, parity, meconium staining, maternal age, spontaneous delivery or cesarean section, meconium passage, weeks of gestation, birth length, body weight, head and chest circumferences, and season, were obtained. The data on sIgE were collected, and a logistic regression model was used to determine the odds of sensitization. Positive sIgE for CM and egg whites was more likely to occur in boys than in girls. Early-life egg white and wheat sensitization was associated with increased birth body length and weight. A multivariate analysis indicated an association between egg white sIgE positivity and logarithmic total IgE. Higher total IgE levels and younger age were associated with egg white sensitization, and elevated weight and length at birth were linked to food sensitization, particularly to egg whites and wheat

Animal science · Biology · Birth weight · Gestation · Logistic regression · Obstetrics · Odds ratio · Pregnancy · Sensitization · Asthma and respiratory diseases · Eosinophilic Esophagitis · Food Allergy and Anaphylaxis Research · Medicine · Immunology · Internal Medicine

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Citations per year0.33
Citation span2023 - 2023 (1)
Highly citedNo

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