Biological activities of endozoic fungi isolated from Biomphalaria alexandrina snails maintained in different environmental conditions
Bibliographic Data
| ID | 19267316 |
|---|---|
| Authors | Marwa Tamim A Abdel‐Wareth (0000-0002-2734-7034, Theodor Bilharz Research Institute, corresponding author), Marwa T A Abdel-Wareth (Theodor Bilharz Research Institute), Ali M El-Hagrassi (National Research Centre), Mohamed S Abdel-Aziz (National Research Centre), Mohamed S Abdel‐Aziz (0000-0001-9151-5920, National Research Centre), Sami Mohamed Nasr (0000-0001-8683-3131, Theodor Bilharz Research Institute), Mosad A Ghareeb (0000-0002-8398-1937, Theodor Bilharz Research Institute) |
| Year | 2019 |
| Volume | 76 |
| Issue | 5 |
| Pages | 780-799 |
| Publication date | 2019-09-03 |
| Open Access | No |
| Type | ARTICLE |
| Venue | International Journal of Environmental Studies (JOURNAL) |
| Journal identifiers | ISSN: 0020-7233 • E-ISSN: 1026-7476 |
| Publisher | Informa UK Limited (PUBLISHER • GB) |
| DOI | 10.1080/00207233.2019.1620535 |
| OpenAlex | W2947889143 |
| Language | EN |
| Citations received | 1 |
| References cited | 58 |
This work aims at studying Biomphalaria alexandrina snails as a source of bioactive compounds. Adult snails were maintained in plastic, mud and cement matrices. Three groups were prepared; under normal laboratory conditions, in slightly low pH conditions, and in high temperature (30°C) conditions. Nine fungal species were isolated from soft tissues of snails. Ethyl acetate and acetone extracts were prepared from each fungal species, and their biological activities were investigated. Paecilomyces variotii extracts were the most effective as antimicrobial agents, while acetone extract of Trichoderma harzianum showed high antioxidant activity. Acetone extracts of Penicillium islandicum and Aspergillus niger were highly active against hepatocellular carcinoma (HepG2) cell lines. Gas chromatography/mass spectrometry analysis of the five effective extracts showed the presence of various compounds. B. alexandrina snails may be regarded as a newly discovered source of beneficial compounds through the metabolites produced by their endozoic fungal strains
Acetone · Antimicrobial · Aspergillus niger · Biological pest control · Biology · Botany · Ethyl acetate · Paecilomyces · Penicillium · Trichoderma harzianum · Biochemistry · Food Science · Fungal Biology and Applications · Microbial Natural Products and Biosynthesis · Microbiology · Phytochemistry and Bioactivity Studies
| Citations per year | 0.33 |
|---|---|
| Citation span | 2023 - 2023 (1) |
| Highly cited | No |