Separation of a compound effective against Biomphalaria alexandrina snails from the filtrate of Penicillium janthinellum
Bibliographic Data
| ID | 19268527 |
|---|---|
| Authors | Abd El-Halim A Saad (,), Magdy T Khalil (,), Tarek M Khalil (0000-0002-5445-9437, Ain Shams University), Fawzy M A Ragab (,), F M Ragab (Theodor Bilharz Research Institute), Amal A I Mekawey (0000-0002-2625-010X, ,), Marwa Tamim A Abdel‐Wareth (0000-0002-2734-7034, Theodor Bilharz Research Institute, corresponding author), Marwa T A Abdel-Wareth (,) |
| Year | 2016 |
| Volume | 73 |
| Issue | 1 |
| Pages | 1-17 |
| Publication date | 2016-01-02 |
| Open Access | No |
| Type | ARTICLE |
| Venue | International Journal of Environmental Studies (JOURNAL) |
| Journal identifiers | ISSN: 0020-7233 • E-ISSN: 1026-7476 |
| Publisher | Informa UK Limited (PUBLISHER • GB) |
| DOI | 10.1080/00207233.2015.1082246 |
| OpenAlex | W2222311899 |
| Language | EN |
| Citations received | 1 |
| References cited | 29 |
Biomphalaria alexandrina snails, as intermediate hosts of schistosomiasis, play a central role in dissemination of the disease. Control of these snails by chemical molluscicides adversely affects the aquatic environment, causing toxic and carcinogenic effects on non-target organisms. Searching for promising substances from biological origin becomes an urgent need to overcome these drawbacks. Screening tests were carried out on 236 fungal genera isolated from the habitat of freshwater snails in four Egyptian governorates. Twenty species were effective against B. alexandrina snails, but the most potent was Penicillium janthinellum as the value of LC50 was 1.03%. Chemical analyses of this filtrate resulted in the separation of a compound effective against snails; it was identified as methyl gallate. Protein electrophoresis showed that both fungal filtrate and methyl gallate affect the protein pattern of snails’ haemolymph. Little or no mortality of Daphnia pulex individuals was observed after their exposure to sub lethal concentrations of each treatment
Biology · Gastropoda · Hemolymph · Snail · Ecology · Identification and Quantification in Food · Mollusks and Parasites Studies · Parasites and Host Interactions · Toxicology
| Citations per year | 0.14 |
|---|---|
| Citation span | 2019 - 2019 (1) |
| Highly cited | No |