Psychologic and Neural Regulation of Growth Hormone Secretion

Bibliographic Data

ID19304367
AuthorsGregory M Brown (0000-0003-3222-9013, Clarke University), Seymour Reichlin (University of Connecticut)
Year1972
Volume34
Issue1
Pages45-61
Publication date1972-01-01
Open AccessNo
TypeARTICLE
VenuePsychosomatic Medicine (JOURNAL)
Journal identifiersISSN: 0033-3174 • E-ISSN: 1534-7796
PublisherOvid Technologies (Wolters Kluwer Health) (PUBLISHER)
DOI10.1097/00006842-197201000-00006
PMID4622682
OpenAlexW2322158431
LanguageEN
Citations received4

A wide variety of stressful stimuli, both physical and psychologic, cause GH discharge in both man and monkey in a manner reminiscent of the changes in ACTH secretion under similar circumstances. The hypothalamus appears to mediate acute changes in GH release as evidenced by the finding that basal hypothalamic or infundibular lesions and pituitary stalk section blocked the acute GH response to hypoglycemia in rat, monkey and man. Changes in GH release in hypoglycemia, prolonged fasting and exercise after meals are related to caloric homeostasis. GH elevation, after stressful stimuli, may produce metabolic effects related to caloric requirements and has protective effects on tissues. The mechanisms for growth hormone release and adrenal corticoid activation are independent since dissociation of these two responses is found after a variety of stimuli in man and monkey. Growth hormone and adrenal discharge appear to have specific independent psychologic correlates

Basal (medicine) · Growth hormone · Homeostasis · Hormone · Hypoglycemia · Hypothalamus · Insulin · Secretion · Adipose Tissue and Metabolism · Diet and metabolism studies · Endocrinology · Growth Hormone and Insulin-like Growth Factors · Internal Medicine · Medicine

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