Social Factors Affecting Emotionality and Resistance to Disease in Animals

V. Early Separation from the Mother and Response to a Transplanted Tumor in the Rat

Bibliographic Data

ID19306704
AuthorsRobert Ader (University of Rochester Medicine), Stanford B Friedman (University of Rochester Medicine)
Year1965
Volume27
Issue2
Pages119-122
Publication date1965-03-01
Peer ReviewedYes
Open AccessNo
TypeARTICLE
VenuePsychosomatic Medicine (JOURNAL)
Journal identifiersISSN: 0033-3174 • E-ISSN: 1534-7796
PublisherOvid Technologies (Wolters Kluwer Health) (PUBLISHER)
DOI10.1097/00006842-196503000-00004
PMID14276917
OpenAlexW2408846378
LanguageEN
Citations received6
References cited1

Seven litters of Sprague-Dawley rats were permanently separated from their mothers at 15 days of age. Five control litters were weaned at the usual time of 21 days. At 45 days animals were inoculated with Walker 256 carcinosarcoma cells. Mortality rate in the early-separated animals was significantly greater than that in the controls. These data increased the generality of the previously reported findings of an increased susceptibility to disease (gastric ulcers) in prematurely weaned rats

Biology · Developmental psychology · Disease · Emotionality · Internal Medicine · Medicine · Neuroendocrine regulation and behavior · Physiology · Psychology

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