Religiosity and treatment response to antidepressant medication
A prospective multi-site clinical trial
Bibliographic Data
| ID | 19504166 |
|---|---|
| Authors | Jonathan R Schettino, Jonathan Schettino (University of California, Los Angeles), Natasha Thapar-Olmos (0000-0003-2773-7849, University of California, Los Angeles), Natasha T Olmos, Hector F Myers (University of California, Los Angeles, corresponding author), Nathan Joseph (0000-0001-8412-5828, University of California, Los Angeles), Nataria T Joseph, Russell E Poland (0000-0003-4395-5811, Meharry Medical College), Ira M Lesser (UCLA Medical Center) |
| Year | 2011 |
| Volume | 14 |
| Issue | 8 |
| Pages | 805-818 |
| Publication date | 2011-10-01 |
| Peer Reviewed | Yes |
| Open Access | No |
| Type | ARTICLE |
| Venue | Mental Health Religion & Culture (JOURNAL) |
| Journal identifiers | ISSN: 1367-4676 • E-ISSN: 1469-9737 |
| Publisher | Informa UK Limited (PUBLISHER • GB) |
| DOI | 10.1080/13674676.2010.527931 |
| PMID | 22736954 |
| PMCID | PMC3380371 |
| OpenAlex | W2052430266 |
| Language | EN |
| Citations received | 6 |
| References cited | 32 |
The present study examined the relationship between religiosity/spirituality and treatment response to antidepressant medication (citalopram). One-hundred and forty-eight Caucasian and African-American adults with uncomplicated major depression were treated with citalopram (20-60mg/day) over an 8-week period in a prospective multi-site clinical trial. Treatment response was assessed weekly with the Hamilton Rating Scale for Depression. Religiosity (i.e., religious behaviours) and spirituality (i.e., spiritual well-being) were assessed at Week 3. No significant associations between spirituality and treatment response were found; however, there was a strong curvilinear relationship between religiosity and treatment response. Compared to lower or higher levels of religiosity, a moderate level of religiosity was significantly associated with a higher likelihood of remission and greater reduction in severity of depression. This association was independent of social support, ethnicity, gender, education, and baseline depression severity. A moderate amount of religiosity appears to be independently associated with an enhanced treatment response to citalopram
Antidepressant · Antidepressant medication · Anxiety · Clinical trial · Psychiatry · Psychotherapist · Religiosity · Cannabis and Cannabinoid Research · Clinical Psychology · Medicine · Mental Health Treatment and Access · Psychology · Religion, Spirituality, and Psychology · Social Psychology · Internal Medicine
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| Unique citing works | 6 |
|---|---|
| Citations per year | 0,46 |
| Citation span | 2013 - 2022 (10) |
| Citation velocity | historical |
| Highly cited | No |
| Citation types | Neutral: 6 |