Recreational Ketamine Use among Individuals with Opioid Use Disorder
Demographics, Motivations, and Polysubstance Use
Bibliographic Data
| ID | 21646206 |
|---|---|
| Authors | Corinne L Chandler (Department of Health, Human Performance & Recreation, University of Arkansas), Mance E Buttram (0000-0002-5001-7391, Department of Health, Human Performance & Recreation, University of Arkansas), Matthew S Ellis (0000-0003-3753-9651, Department of Psychiatry, Washington University in St. Louis School of Medicine, corresponding author) |
| Year | 2025 |
| Volume | 60 |
| Issue | 9 |
| Pages | 1375-1381 |
| Publication date | 2025-07-29 |
| Peer Reviewed | Yes |
| Open Access | No |
| Type | ARTICLE |
| Venue | Substance Use & Misuse (JOURNAL) |
| Journal identifiers | ISSN: 1082-6084 • E-ISSN: 1532-2491 |
| Publisher | Informa UK Limited (PUBLISHER • GB) |
| DOI | 10.1080/10826084.2025.2497950 |
| PMID | 40312922 |
| OpenAlex | W4410042630 |
| Language | EN |
| References cited | 35 |
BACKGROUND: Data show that recreational ketamine use appears to be increasing. This study aimed to understand how ketamine fits into broader polysubstance use in individuals with opioid use disorder (OUD). METHODS: Survey data were collected from a sample of treatment-seeking individuals with OUD in March 2022. RESULTS: < 0.002). Most respondents (70.9%) used ketamine to achieve a desired psychoactive effect, and 46.4% used to self-treat a physical or mental health problem, including mental distress symptoms and mitigating opioid withdrawal symptoms or cravings. Polysubstance use involving ketamine was prevalent (70.7%) and included marijuana (64.9%), alcohol (61.4%), cocaine (36.8%), MDMA (36.8%), hallucinogens (31.6%), prescription opioids (29.8%), and illicit opioids (29.8%). Negative experiences while using ketamine were reported by 32.1% and included central nervous system complications and mental distress. CONCLUSIONS: Among this sample of individuals with OUD, motivations for ketamine use are varied and polysubstance use is common. Such behaviors, even when attempting to self-treat OUD or other health problems may place individuals at risk for psychiatric or physical health conditions, including overdose or death
Demographics · Drug · Ketamine · Opioid · Opioid use disorder · Polysubstance dependence · Psychiatry · Recreation · Recreational Drug · Recreational use · Substance abuse · Clinical Psychology · Demography · Forensic Toxicology and Drug Analysis · Medicine · Opioid Use Disorder Treatment · Psychology · Treatment of Major Depression · Internal Medicine
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| Citation velocity | historical |
|---|---|
| Highly cited | No |