The association between perchlorate in drinking water and height and weight of children and adolescents in Southwest China

A retrospective cross-sectional study

Bibliographic Data

ID22083204
AuthorsHongyu Guo (0000-0003-2522-6324), Guo Hongyu (0000-0002-6969-5424, Sichuan Center for Disease Control and Prevention), Shimiao Zong, Shi Zong (0000-0003-2521-7452, Chengdu Medical College), Li Yong (0000-0002-6838-7841, Sichuan Center for Disease Control and Prevention), Yang Jiang (0000-0002-9193-6888, Sichuan Center for Disease Control and Prevention), Ling Qin (0009-0005-6386-0512, Sichuan Center for Disease Control and Prevention), Liang Zhou (0000-0003-4374-2242, Sichuan Center for Disease Control and Prevention), Qiaoqiao Ren (0000-0001-5561-1747, Sichuan Center for Disease Control and Prevention), Xufang Gao (Chengdu Center for Disease Control and Prevention), Fayang Kang, Wei Huang (0000-0002-5095-3972, Zigong First People's Hospital), Jianyu Chen (0000-0001-5893-2116, Sichuan Center for Disease Control and Prevention, corresponding author), Li Zhang (0000-0002-4441-5131, Sichuan Center for Disease Control and Prevention, corresponding author)
Year2023
Volume11
Pages1260612-1260612
Publication date2023-10-04
Open AccessYes
TypeARTICLE
VenueFrontiers in Public Health (JOURNAL)
Journal identifiersISSN: 2296-2565 • E-ISSN: 2296-2565
PublisherFrontiers Media SA (PUBLISHER • CH)
DOI10.3389/fpubh.2023.1260612
PMID37860794
OpenAlexW4387335504
LanguageEN
References cited39

Objective To investigate the association between the concentration of perchlorate in drinking water and the height and weight of children and adolescents in Sichuan Province. Methods Perchlorate in the drinking water of 24 counties in Sichuan Province from 2021 to 2022 was detected and analyzed, 66 drinking water samples were collected, and the content of perchlorate in drinking water during the wet season and dry season was detected by ultra-high performance liquid chromatography in series. The linear mixed effect model was used to estimate the relationship between perchlorate in drinking water and the height and weight of 144,644 children and adolescents, and 33 pieces of local average wage data were used as confounding factors for quality control. Results After controlling the age, gender, and local economic situation, we found that the concentration of perchlorate in drinking water increased by 10 μg/L is associated with a 1.0 cm decrease in height and a 1.6 kg decrease in weight in children and adolescents ( p < 0.05). Conclusion The concentration of perchlorate in drinking water may be negatively correlated with the height and weight of children

Animal science · Biology · Confounding · Cross-sectional study · Environmental health · Perchlorate · Water quality · Chemical Analysis and Environmental Impact · Chemistry · Demography · Effects and risks of endocrine disrupting chemicals · Medicine · Per- and polyfluoroalkyl substances research · Internal Medicine

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