Vitamin D
A Potential Mitigation Tool for the Endemic Stage of the Covid-19 Pandemic
Bibliographic Data
| ID | 22085299 |
|---|---|
| Authors | Daniela Briceno Noriega (0000-0002-4909-2976, Wageningen University & Research, corresponding author), Huub F J Savelkoul (0000-0001-6236-7092, Wageningen University & Research) |
| Year | 2022 |
| Volume | 10 |
| Pages | 888168-888168 |
| Publication date | 2022-06-10 |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | Frontiers in Public Health (JOURNAL) |
| Journal identifiers | ISSN: 2296-2565 • E-ISSN: 2296-2565 |
| Publisher | Frontiers Media SA (PUBLISHER • CH) |
| DOI | 10.3389/fpubh.2022.888168 |
| PMID | 35757617 |
| OpenAlex | W4281770808 |
| Language | EN |
| References cited | 152 |
The impact of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic and associated development of clinical symptoms of COVID-19 have presented an enormous global impact on our health care systems, public health and economy. To date several observational epidemiological studies consistently found that vitamin D deficiency, measured as low levels of circulating 25-hydroxyvitamin D, is associated with cardiovascular diseases, diabetes, certain cancers, autoimmune diseases and many infectious diseases, including acute respiratory infections. Since vitamin D is not merely immunosuppressive but also acts as an immunomodulator in tolerance and homeostasis, many experts have considered a role of vitamin D in the prevalence and severity of immune mediated inflammatory diseases, such as SARS-CoV-2, adding to the evidence of the importance of vitamin D in the immune response against viral respiratory infections and reinforcing the need for targeted vitamin D supplementation, with a focus on high-risk populations and a high-dose supplementation treatment for COVID-19 hospitalized patients. The expected transition to endemicity of SARS-CoV-2 even further corroborates as a potential of vitamin D as an potential mitigation tool for the prevention of COVID-19. The aim of this paper is to analyse the current evidence regarding vitamin D and present a hypothesis of its potential role in the current COVID-19 pandemic and in the future as a potential preventive measurement in public health
Coronavirus · Diabetes mellitus · Disease · Immune system · Intensive care medicine · Pandemic · Pathology · Public health · Vitamin D and neurology · vitamin D deficiency · COVID-19 Clinical Research Studies · Medicine · Vitamin C and Antioxidants Research · Vitamin D Research Studies · Endocrinology · Epidemiology · Immunology · Internal Medicine
| Highly cited | No |
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