Mitochondrial DNA (CA)n dinucleotide repeats in Muslims from South India

Bibliographic Data

ID2640938
AuthorsSomayyeh Samehsalari (0000-0001-5232-0952, University of Mysore), K Rajasekhara Reddy (University of Mysore)
Year2019
Volume2
Issue12
Pages142
Publication date2019-09-13
Open AccessYes
TypeARTICLE
VenueInternational Journal of Modern Anthropology (JOURNAL)
Journal identifiersISSN: 1737-7374 • E-ISSN: 1737-8176
PublisherAfrican Journals Online (AJOL) (PUBLISHER)
DOI10.4314/ijma.v2i12.6
OpenAlexW2973189780
LanguageEN
Citations received1
References cited4

We have studied the variability of the CA repeats in HVIII region of mitochondrial DNA among 60 unrelated Muslims of Srirangapatna town, Karnataka state in South India. MtDNA HVIII region was amplified and sequenced by Sanger sequencing method. A total of four alleles [(CA)4 to (CA)7 ] were detected and (CA)5 rCRS repeat was the most frequently defined repeat followed by (CA)4 28%, (CA)6 16%, (CA)7 15%. A statistical estimate indicated a high genetic diversity of 0.7218 and a low random mach probability of 0.2903, and the discrimination power calculated was 0.7097. Compared with those obtained in other explored world populations our data support the significance application of HVIII CA repeat polymorphism of mitochondrial DNA in the genetic differentiation of human populations and forensic investigation casework.Keywords: Mitochondrial, HVIII, (CA)n repeats, Muslim, South India

Allele · Biology · DNA · DNA sequencing · Gene · Mitochondrial DNA · Sanger sequencing · Forensic and Genetic Research · Genetics · Mitochondrial Function and Pathology · Molecular Biology · Yersinia bacterium, plague, ectoparasites research

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