Improving survival in children with Aids in Brazil

Results of the Second National Study, 1999-2002

Bibliographic Data

ID5229131
AuthorsLuiza Harunari Matida (Secretaria de Estado da Saúde de São Paulo, Brasil), Alberto Novaes Ramos (0000-0001-7982-1757, Universidade Federal do Ceará), Alberto Novaes Ramos Jr (Universidade Federal do Ceará), Jorg Heukelbach (0000-0002-7845-5510, Universidade Federal do Ceará), Adriana Sanudo (0000-0003-1187-0143, Universidade de São Paulo), Regina Célia De Menezes Succi (0000-0003-4522-6292, Universidade Federal de São Paulo), Heloísa Helena De Sousa Marques (0000-0002-0940-7793, Universidade de São Paulo), Marinella Della Negra (University of California System), Norman Hearst (0000-0003-1218-9173, University of California, San Francisco)
Year2011
Volume27
Issuesuppl 1
Pagess93-s103
Publication date2011-01-01
Open AccessYes
TypeARTICLE
VenueCadernos de Saude Publica (JOURNAL)
Journal identifiersISSN: 0102-311X • E-ISSN: 1678-4464
PublisherFapUNIFESP (SciELO) (PUBLISHER)
DOI10.1590/s0102-311x2011001300010
PMID21503529
OpenAlexW1666642131
SciELOS0102-311X2011001300010
LanguageEN
Citations received4
References cited31

The objective of this study is to characterize survival in children with AIDS diagnosed in Brazil between 1999-2002, compared with the first national study (1983-1998). This national retrospective cohort study examined a representative sample of Brazilian children exposed to HIV from mother-to-child transmission and followed through 2007. The survival probability after 60 months was analyzed by sex, year of birth and death, clinical classification, use of antiretroviral therapy (ART) and prophylaxis for opportunistic diseases. 920 children were included. The survival probability increased: comparing cases diagnosed before 1988 with those diagnosed from 2001-2002 it increased by 3.5-fold (from 25% to 86.3%). Use of ART, initial clinical classification, and final classification were significant (p < 0.001) predictors of survival. Issues regarding quality of records and care were identified. The results point to the success of the Brazilian policy of providing ART. The improvement of clinical status contributes to quality of life, while indicating challenges, particularly practices to improve long-term care

Cohort · Family medicine · Human immunodeficiency virus (HIV) · Retrospective cohort study · Survival analysis · Demography · HIV-related health complications and treatments · HIV/AIDS Research and Interventions · Internal Medicine · Medicine · Poverty, Education, and Child Welfare · Pediatrics

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