Demographic and Genetic Structures of Two Partially Isolated Communities of Santa Catarina Island, Southern Brazil

Bibliographic Data

ID6068477
AuthorsIliada Rainha De Souza (Universidade Federal de Santa Catarina), Yara Costa Netto Muniz (0000-0001-9526-8306), Gabriela De Medeiros Saldanha, Leonardo Alves (0000-0003-4184-7083), Fabiana Cristiane Da Rosa, Felipe A B Maegawa, Felipe B Maegawa (0000-0002-3289-6054), Michele F Susin, Melissa De Souza Lipinski, M Luiza Petzl‐erler (0000-0002-0345-5276), Maria Luiza Petzl-Erler
Year2003
Volume75
Issue2
Pages241-253
Publication date2003-01-01
Peer ReviewedYes
Open AccessNo
TypeARTICLE
VenueHuman Biology (JOURNAL)
Journal identifiersISSN: 0018-7143 • E-ISSN: 1534-6617
PublisherProject MUSE (PUBLISHER • US)
DOI10.1353/hub.2003.0038
PMID12943161
OpenAlexW1976701551
LanguageEN
Citations received2
References cited9

The objectives of this study were to analyze the population structure and genetic variability of two communities, Costa da Lagoa (CLG) and São João do Rio Vermelho (SJRV), located on Santa Catarina Island in southern Brazil. The two populations descend from Azores Archipelago immigrants (Portuguese), with a minor contribution of sub-Saharan Africans and Amerindians. To estimate the relative contribution of the different ethnic groups to the current gene pool of the two communities, values of admixture were obtained using the weighted least-squares method based on allelic frequencies of the loci ABO, RHD-RHCE, GPA-GPB (MNSs), HBB, HP, TF, CP, AK, and ACP1. The origins of the studied populations can be quantified as follows: for CLG, sub-Saharan Africans (A) = 17.3%, Iberian Europeans (P) = 75.0%, and Southern Amerindians (I) = 7.7%; for SJRV, A = 48.8%, P = 44.5%, and I = 6.7%. Because haplotype frequencies of the GPA-GPB loci in SJRV were unusual, possibly as a consequence of random genetic drift, the values of admixture were recalculated after exclusion of GPA-GPB, as follows: A = 28.0%; P = 53.3%, and I = 18.7%. The total diversity (HT) was estimated as 42.29%, of which 99.6% can be attributed to the intrapopulational variability (HS). The interpopulational genetic variation (or standard distance, DST) corresponds to 0.19%, while the gene differentiation coefficient is 0.28%, indicative of low genetic difference. These results led to the conclusion that random genetic drift may have had an important effect on the Costa da Lagoa community, while presently gene flow might be the predominant evolutionary factor potentially capable of changing allele frequencies in SJRV

ABO blood group system · Allele · Archipelago · Biology · Founder effect · Gene · Gene pool · Genetic distance · Genetic diversity · Genetic drift · Genetic variability · Genetic variation · Genotype · Geographical distance · Geography · Haplotype · Population · Chromosomal and Genetic Variations · Demography · Ecology · Forensic and Genetic Research · Genetic diversity and population structure · Genetics

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