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Investigation of the link between visceral surface rib lesions and tuberculosis in a Medieval skeletal series from England using ancient DNA

Bibliographic Data

ID8312947
AuthorsS Mays (English Heritage, corresponding author), Edward Fysh (0000-0003-1126-3773, St Mary's Hospital), G Michael Taylor (0000-0002-4215-3916, Imperial College London)
Year2002
Volume119
Issue1
Pages27-36
Publication date2002-09-01
Peer ReviewedYes
Open AccessYes
TypeARTICLE
VenueAmerican Journal of Physical Anthropology (JOURNAL)
Journal identifiersISSN: 0002-9483 • E-ISSN: 1096-8644
PublisherWiley (PUBLISHER • GB)
DOI10.1002/ajpa.10099
PMID12209571
OpenAlexW2082162780
LanguageEN
Citations received43
References cited41

Seven human skeletons from a large assemblage from a rural English Medieval burial site show lesions, predominantly proliferative in nature, on the visceral surfaces of the ribs. In order to investigate whether these rib lesions were regularly associated with tuberculous infection, these individuals, together with a group of age‐ and sex‐matched control skeletons without bony signs of infection, were subjected to polymerase chain reaction (PCR) assays aimed at detecting traces of DNA from infecting microorganisms of the Mycobacterium tuberculosis complex. The results provided no evidence for any regular association between visceral surface rib lesions and the presence of M. tuberculosis complex DNA in the study group. The significance of these findings for the paleopathological interpretation of visceral surface rib lesions is discussed. Am J Phys Anthropol 119:27–36, 2002. © 2002 Wiley‐Liss, Inc

Ancient DNA · Biology · Gene · Mycobacterium tuberculosis · Mycobacterium tuberculosis complex · Nested polymerase chain reaction · Paleopathology · Pathology · Polymerase chain reaction · Population · Rib cage · Tuberculosis · Anatomy · Forensic Anthropology and Bioarchaeology Studies · Genetics · Infectious Diseases and Tuberculosis · Medicine · Oral Health Pathology and Treatment

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Unique citing works43
Citations per year1,95
Citation span2004 - 2026 (23)
Citation velocitycurrent
Highly citedNo
Citation typesNeutral: 38

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