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Paleopathological and biomolecular study of tuberculosis in a medieval skeletal collection from England

Bibliographic Data

ID8319296
AuthorsMay (0000-0002-0352-5625), S Mays (English Heritage, corresponding author), G Michael Taylor (0000-0002-4215-3916), A J Legge (Birkbeck, University of London), D Young (0000-0001-8942-0308), D B Young, G Turner‐walker (0000-0001-7728-402X, Norwegian University of Science and Technology)
Year2001
Volume114
Issue4
Pages298-311
Publication date2001-04-01
Peer ReviewedYes
Open AccessYes
TypeARTICLE
VenueAmerican Journal of Physical Anthropology (JOURNAL)
Journal identifiersISSN: 0002-9483 • E-ISSN: 1096-8644
PublisherWiley (PUBLISHER • GB)
DOI10.1002/ajpa.1042
PMID11275959
OpenAlexW2110484113
LanguageEN
Citations received54
References cited43

Nine human skeletons of medieval date from a rural English burial site show signs of skeletal tuberculosis. They were subject to polymerase chain reaction (PCR) assays aimed at detecting traces of DNA from infecting mycobacteria, with the purpose both of confirming the paleopathological diagnosis of tuberculosis and determining in individual cases whether disease was due to M. tuberculosis or M. bovis . In all nine cases, evidence for M. tuberculosis complex DNA was found, and in all instances it appeared that disease was due to M. tuberculosis rather than M. bovis . The significance of the findings for understanding tuberculous infection in rural agrarian communities in medieval England is discussed. Am J Phys Anthropol 114:298–311, 2001. © 2001 Wiley‐Liss, Inc

Ancient DNA · Archaeology · Biology · Disease · Environmental health · Gene · Geography · Mycobacterium bovis · Mycobacterium tuberculosis · Paleopathology · Pathology · Polymerase chain reaction · Population · Tuberculosis · Genetics · Infectious Diseases and Tuberculosis · Medicine · Mycobacterium research and diagnosis · Tuberculosis Research and Epidemiology

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Unique citing works54
Citations per year2,25
Citation span2002 - 2026 (25)
Citation velocitycurrent
Highly citedNo
Citation typesNeutral: 49

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