Alla Sikorskii
Biographic Data
| ID | 1302840 |
|---|---|
| NAME | Alla Sikorskii |
| GIVEN NAMES | Alla |
| FAMILY NAME | Sikorskii |
| SIGNATURE | SIKORSKII A |
| AFFILIATIONS | Michigan State University |
| ORCID | 0000-0002-4121-1627 |
| VERIFIED | Yes |
| TOTAL WORKS | 19 |
| TOTAL CITATIONS | 0 |
| AUTHOR COUNT | 19 |
| EDITOR COUNT | 0 |
| FIRST PUBLICATION YEAR | 2009 |
| LATEST PUBLICATION YEAR | 2025 |
| H-INDEX | 0 |
Perinatal HIV exposure and infection and child executive function
In the combined antiretroviral therapy era, limited information exists about cognitive function in children exposed perinatally to human immunodeficiency virus (HIV). To address this, we evaluated executive function (EF) among groups with known HIV exposure status during the perinatal period and at ages 6–10 years: children HIV-infected perinatally (CPHIV, n = 99), children born to HIV-infected mothers, but were HIV negative at enrollment (CPHEU,…
Association of adult caregiver depression with developmental disorder likelihood in Ugandan children perinatally exposed and unexposed to HIV
We assessed whether higher caregiver depression is associated with increased likelihood of caregivers rating their children as screening positive for developmental disorders—autism spectrum disorder (ASD), attention-deficit/hyperactivity disorder, emotional behavioral disorder, and functional impairment (FI)—among Ugandan children perinatally exposed and unexposed to HIV. Children and their primary caregivers were followed for 12 months. Caregive…
Perinatal HIV exposure and infection and caregiver depressive symptoms
Survival is possible for children perinatally exposed to or infected by HIV in the post-combined antiretroviral therapy era and identifying factors affecting children’s ability to thrive has public health significance. Caregiver mental health is one such factor to consider given its impact on child development, but previous work has not included a full complement of HIV exposure/infection groups within HIV-endemic settings. We compared depressive…
Predictors of persistence of post-chemotherapy symptoms among survivors of solid tumor cancers
Depression among underserved rural and urban caregivers of Latinas with breast cancer
Among Latino/as, informal caregiving duties are often deemed a family responsibility. Understanding psychological outcomes tied to caregivers of Latina breast cancer survivors is important to identify the impacts of cancer. Secondary analysis of baseline data collected in a randomized clinical trial (RCT) from 230 Latina breast cancer survivor-caregiver dyads. Characteristics of caregivers residing in rural/underserved and urban areas were compar…
Developmental Disorder Probability Scores at 6–18 Years Old in Relation to In-Utero/Peripartum Antiretroviral Drug Exposure among Ugandan Children
(1) We examined the hypothesis that in utero/peripartum antiretroviral (IPA) exposure may affect the likelihood of developmental disorders-i.e., attention deficit and hyperactivity disorder (ADHD), autism spectrum disorder (ASD), and functional impairment (FI). (2) Children and their primary caregivers were enrolled and followed for 12 months. The sample included 250 children perinatally HIV-infected (CPHIV), 250 children HIV-exposed and uninfect…
Association of serum Pufa and linear growth over 12 months among 6–10 years old Ugandan children with or without HIV
Objective: To quantify PUFA-associated improvement in linear growth among children aged 6–10 years. Design: Serum fatty acids (FA), including essential FA (EFA) (linoleic acid (LA) and α -linolenic acid (ALA)) were quantified at baseline using GC-MS technology. FA totals by class ( n -3, n-6, n -9, PUFA and SFA) and FA ratios were calculated. Height-for-age Z -score (HAZ) relative to WHO population reference values were calculated longitudinally …
Informal caregiver burden for solid tumour cancer patients: A review and future directions
OBJECTIVE: Recent shifts in healthcare delivery and treatment for solid tumour cancer patients have modified the responsibilities of informal caregivers. The objective of this study was to: review informal caregiver burden factors and determine areas where future research is needed. METHODS: The Arksey and O'Malley's framework and a modified Preferred Reporting Items for Systematic Reviews and Meta-Analyses were used in conducting this review. Re…
The Relationship Between Health-Related Quality of Life and Saliva C-Reactive Protein and Diurnal Cortisol Rhythm in Latina Breast Cancer Survivors and Their Informal Caregivers: A Pilot Study
Introduction: To date, no study has explored associations between objective stress-related biomarkers (i.e., inflammatory markers, diurnal rhythm of cortisol) and health-related quality of life (HRQOL) in Latina breast cancer survivors and their informal caregivers (i.e., family, friends). Method: This cross-sectional feasibility study assessed saliva C-reactive protein, saliva diurnal cortisol rhythm (cortisol slope), and self-reported HRQOL (ps…
Psychological Distress and Social Support Availability in Different Family Caregivers of Latinas With Breast Cancer
Introduction: Latinas with breast cancer draw on a diverse range of family members for informal care. Latin cultures typically prescribe high levels of support and care for an ill family member that leave caregivers vulnerable to compromised well-being. Method: In this cross-sectional survey study, 258 family caregivers of Latinas with breast cancer completed reports of psychological distress, availability of social support, and acculturation. Re…
Longitudinal Dyadic Interdependence in Depression Symptoms of Caregivers Living with HIV in Uganda and Their Dependent Children’s Neurodevelopment and Executive Behavior Outcomes
Economic evaluation of a farm-to-Special Supplemental Nutrition Programme for Women, Infants and Children intervention promoting vegetable consumption
Objective: To evaluate the cost and cost-effectiveness of a farm-to-Special Supplemental Nutrition Programme for Women, Infants and Children (WIC) intervention to promote vegetable intake and the redemption of WIC vouchers for produce purchases at farmers’ markets. Design: An economic analysis was undertaken using data from a pilot of the intervention. Vegetable intake was assessed with a reflection spectroscopy device (the Veggie Meter® [VM]) an…
Toxic Stress and Quality of Life in Early School‐Aged Ugandan Children With and Without Perinatal Human Immunodeficiency Virus Infection
Caregiver's and child's self-reported quality of life (QOL) was defined using standardized questionnaires in a sample (N = 277) of 6-10 years old HIV-infected, HIV-exposed uninfected, and HIV-unexposed uninfected children from Uganda. Psychosocial stress (acute stress and cumulative lifetime adversity) and physiologic stress (dysregulations across 13 biomarkers), perinatal HIV status, and their interaction were related to child QOL via general li…
Psychosocial Adjustment in Ugandan Children: Coping With Human Immunodeficiency Virus Exposure, Lifetime Adversity, and Importance of Social Support
Cumulative lifetime adversity and social support were investigated as determinants of psychosocial adjustment (esteem, distress, hopefulness, positive outlook/future aspirations, and sense of purpose) over 12 months in 6-10-years-old HIV-infected, HIV-exposed uninfected and HIV-unexposed uninfected children from Uganda. Each determinant and psychosocial adjustment indicator was self-reported using standardized questionnaires administered at basel…
Depression Symptom Trajectories Among Mothers Living with HIV in Rural Uganda
Association of caregiver quality of care with neurocognitive outcomes in HIV-affected children aged 2–5 years in Uganda
Children affected by HIV are at increased risk of developmental and neuropsychological disturbances due to direct effects of HIV on the brain and direct effects associated with living in poverty. Caregivers can play an important role, through quality caregiving, in mitigating the negative effect of these stressors. This study used baseline data from an ongoing caregiver training intervention trial to evaluate the association between quality of ca…
Socio-demographic correlates of depression and anxiety among female caregivers living with HIV in rural Uganda
Women living with HIV are at increased risk for psychosocial distress, especially among social and economically disadvantaged women living in rural areas. Little is known about how social support and wealth impacts the mental health of women caring for young children in low- and middle-income countries. The purpose of this paper was to assess demographic, socio-economic, and social support correlates of depression and anxiety in HIV-infected+ fem…
Designing and evaluating Brain Powered Games for cognitive training and rehabilitation in at-risk African children
Results provide preliminary support for the acceptability, feasibility, and neurocognitive benefit of BPG and its utility as a model platform for computerized cognitive training in cross-cultural low-resource settings
Differential Symptom Reporting by Mode of Administration of the Assessment: Automated Voice Response System Versus a Live Telephone Interview
BACKGROUND: Automated voice response (AVR) systems have been used to collect patient-reported outcome data. Mode of administration of the assessment may affect patient reporting. OBJECTIVE: To evaluate if there is a differential reporting of symptoms by the mode of assessment: AVR versus a live telephone interview among cancer patients with solid tumors undergoing chemotherapy. RESEARCH DESIGN: Randomized clinical trial comparing a nurse-assisted…
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Differential Symptom Reporting by Mode of Administration of the Assessment: Automated Voice Response System Versus a Live Telephone Interview
BACKGROUND: Automated voice response (AVR) systems have been used to collect patient-reported outcome data. Mode of administration of the assessment may affect patient reporting. OBJECTIVE: To evaluate if there is a differential reporting of symptoms by the mode of assessment: AVR versus a live telephone interview among cancer patients with solid tumors undergoing chemotherapy. RESEARCH DESIGN: Randomized clinical trial comparing a nurse-assisted…
Designing and evaluating Brain Powered Games for cognitive training and rehabilitation in at-risk African children
Results provide preliminary support for the acceptability, feasibility, and neurocognitive benefit of BPG and its utility as a model platform for computerized cognitive training in cross-cultural low-resource settings
Association of caregiver quality of care with neurocognitive outcomes in HIV-affected children aged 2–5 years in Uganda
Children affected by HIV are at increased risk of developmental and neuropsychological disturbances due to direct effects of HIV on the brain and direct effects associated with living in poverty. Caregivers can play an important role, through quality caregiving, in mitigating the negative effect of these stressors. This study used baseline data from an ongoing caregiver training intervention trial to evaluate the association between quality of ca…
Socio-demographic correlates of depression and anxiety among female caregivers living with HIV in rural Uganda
Women living with HIV are at increased risk for psychosocial distress, especially among social and economically disadvantaged women living in rural areas. Little is known about how social support and wealth impacts the mental health of women caring for young children in low- and middle-income countries. The purpose of this paper was to assess demographic, socio-economic, and social support correlates of depression and anxiety in HIV-infected+ fem…
Depression Symptom Trajectories Among Mothers Living with HIV in Rural Uganda
Toxic Stress and Quality of Life in Early School‐Aged Ugandan Children With and Without Perinatal Human Immunodeficiency Virus Infection
Caregiver's and child's self-reported quality of life (QOL) was defined using standardized questionnaires in a sample (N = 277) of 6-10 years old HIV-infected, HIV-exposed uninfected, and HIV-unexposed uninfected children from Uganda. Psychosocial stress (acute stress and cumulative lifetime adversity) and physiologic stress (dysregulations across 13 biomarkers), perinatal HIV status, and their interaction were related to child QOL via general li…
Psychosocial Adjustment in Ugandan Children: Coping With Human Immunodeficiency Virus Exposure, Lifetime Adversity, and Importance of Social Support
Cumulative lifetime adversity and social support were investigated as determinants of psychosocial adjustment (esteem, distress, hopefulness, positive outlook/future aspirations, and sense of purpose) over 12 months in 6-10-years-old HIV-infected, HIV-exposed uninfected and HIV-unexposed uninfected children from Uganda. Each determinant and psychosocial adjustment indicator was self-reported using standardized questionnaires administered at basel…
Informal caregiver burden for solid tumour cancer patients: A review and future directions
OBJECTIVE: Recent shifts in healthcare delivery and treatment for solid tumour cancer patients have modified the responsibilities of informal caregivers. The objective of this study was to: review informal caregiver burden factors and determine areas where future research is needed. METHODS: The Arksey and O'Malley's framework and a modified Preferred Reporting Items for Systematic Reviews and Meta-Analyses were used in conducting this review. Re…
The Relationship Between Health-Related Quality of Life and Saliva C-Reactive Protein and Diurnal Cortisol Rhythm in Latina Breast Cancer Survivors and Their Informal Caregivers: A Pilot Study
Introduction: To date, no study has explored associations between objective stress-related biomarkers (i.e., inflammatory markers, diurnal rhythm of cortisol) and health-related quality of life (HRQOL) in Latina breast cancer survivors and their informal caregivers (i.e., family, friends). Method: This cross-sectional feasibility study assessed saliva C-reactive protein, saliva diurnal cortisol rhythm (cortisol slope), and self-reported HRQOL (ps…
Psychological Distress and Social Support Availability in Different Family Caregivers of Latinas With Breast Cancer
Introduction: Latinas with breast cancer draw on a diverse range of family members for informal care. Latin cultures typically prescribe high levels of support and care for an ill family member that leave caregivers vulnerable to compromised well-being. Method: In this cross-sectional survey study, 258 family caregivers of Latinas with breast cancer completed reports of psychological distress, availability of social support, and acculturation. Re…
Longitudinal Dyadic Interdependence in Depression Symptoms of Caregivers Living with HIV in Uganda and Their Dependent Children’s Neurodevelopment and Executive Behavior Outcomes
Economic evaluation of a farm-to-Special Supplemental Nutrition Programme for Women, Infants and Children intervention promoting vegetable consumption
Objective: To evaluate the cost and cost-effectiveness of a farm-to-Special Supplemental Nutrition Programme for Women, Infants and Children (WIC) intervention to promote vegetable intake and the redemption of WIC vouchers for produce purchases at farmers’ markets. Design: An economic analysis was undertaken using data from a pilot of the intervention. Vegetable intake was assessed with a reflection spectroscopy device (the Veggie Meter® [VM]) an…
Developmental Disorder Probability Scores at 6–18 Years Old in Relation to In-Utero/Peripartum Antiretroviral Drug Exposure among Ugandan Children
(1) We examined the hypothesis that in utero/peripartum antiretroviral (IPA) exposure may affect the likelihood of developmental disorders-i.e., attention deficit and hyperactivity disorder (ADHD), autism spectrum disorder (ASD), and functional impairment (FI). (2) Children and their primary caregivers were enrolled and followed for 12 months. The sample included 250 children perinatally HIV-infected (CPHIV), 250 children HIV-exposed and uninfect…
Association of serum Pufa and linear growth over 12 months among 6–10 years old Ugandan children with or without HIV
Objective: To quantify PUFA-associated improvement in linear growth among children aged 6–10 years. Design: Serum fatty acids (FA), including essential FA (EFA) (linoleic acid (LA) and α -linolenic acid (ALA)) were quantified at baseline using GC-MS technology. FA totals by class ( n -3, n-6, n -9, PUFA and SFA) and FA ratios were calculated. Height-for-age Z -score (HAZ) relative to WHO population reference values were calculated longitudinally …
Depression among underserved rural and urban caregivers of Latinas with breast cancer
Among Latino/as, informal caregiving duties are often deemed a family responsibility. Understanding psychological outcomes tied to caregivers of Latina breast cancer survivors is important to identify the impacts of cancer. Secondary analysis of baseline data collected in a randomized clinical trial (RCT) from 230 Latina breast cancer survivor-caregiver dyads. Characteristics of caregivers residing in rural/underserved and urban areas were compar…
Perinatal HIV exposure and infection and caregiver depressive symptoms
Survival is possible for children perinatally exposed to or infected by HIV in the post-combined antiretroviral therapy era and identifying factors affecting children’s ability to thrive has public health significance. Caregiver mental health is one such factor to consider given its impact on child development, but previous work has not included a full complement of HIV exposure/infection groups within HIV-endemic settings. We compared depressive…
Predictors of persistence of post-chemotherapy symptoms among survivors of solid tumor cancers
Perinatal HIV exposure and infection and child executive function
In the combined antiretroviral therapy era, limited information exists about cognitive function in children exposed perinatally to human immunodeficiency virus (HIV). To address this, we evaluated executive function (EF) among groups with known HIV exposure status during the perinatal period and at ages 6–10 years: children HIV-infected perinatally (CPHIV, n = 99), children born to HIV-infected mothers, but were HIV negative at enrollment (CPHEU,…
Association of adult caregiver depression with developmental disorder likelihood in Ugandan children perinatally exposed and unexposed to HIV
We assessed whether higher caregiver depression is associated with increased likelihood of caregivers rating their children as screening positive for developmental disorders—autism spectrum disorder (ASD), attention-deficit/hyperactivity disorder, emotional behavioral disorder, and functional impairment (FI)—among Ugandan children perinatally exposed and unexposed to HIV. Children and their primary caregivers were followed for 12 months. Caregive…
Medicine (16 works) · Psychiatry (13 works) · Psychology (10 works) · Clinical Psychology (9 works) · Internal Medicine (7 works) · Psychological intervention (7 works) · Cancer survivorship and care (6 works) · Maternal Mental Health During Pregnancy and Postpartum (6 works) · Poverty, Education, and Child Welfare (6 works) · Cancer (5 works)