Ella M Nikulina
Biographic Data
| ID | 6109173 |
|---|---|
| NAME | Ella M Nikulina |
| GIVEN NAMES | Ella M |
| FAMILY NAME | Nikulina |
| SIGNATURE | NIKULINA E M |
| AFFILIATIONS | Institute of Cytology and Genetics |
| ORCID | 0000-0003-0788-4665 |
| VERIFIED | Yes |
| TOTAL WORKS | 6 |
| TOTAL CITATIONS | 0 |
| WORKS AS AUTHOR | 6 |
| WORKS AS EDITOR | 0 |
| FIRST PUBLICATION YEAR | 1986 |
| LATEST PUBLICATION YEAR | 1994 |
| H-INDEX | 0 |
Defensive reactions of “wild-type” and “Domesticated” wild rats to approach and contact by a threat stimulus
Selective breeding of wild rats over many generations on the basis of low or high defensive threat and attack to human approach and contact has produced highly polarized “domesticated” and “wild-type” animals. Because the selection procedure selectively involves these two defense patterns, and these clearly differ in the two groups, it is of interest to determine if other, nonselected, defensive behaviors to threat stimuli also change. “Domestica…
Role of 5HT1A receptors in a variety of kinds of aggressive behavior in wild rats and counterparts selected for low defensiveness towards man
The 5HT1A receptor agonist ipsapirone (10 mg/kg) suppressed shock-induced aggression in wild and domesticated rats but did not affect predatory aggression in either group of animals. Ipsapirone decreased neophobia and inhibited defensive reactions by wild rats towards man in the glove test. [3H]8-OH-DPAT binding, which labels 5HT1A receptors, was significantly increased in the hypothalamus of domesticated rats in comparison with wild counterparts…
Selection for reduced aggressiveness towards man and dopaminergic activity in Norway rats
The brain dopaminergic system is involved in the process of long-term selection for reduced aggressive reaction towards man in Norway rats. The dopamine levels in the striatum as well as the nucleus accumbens with the tuberculum olfactorium were significantly lower in domesticated rats than in their wild counterparts. A substantial decrease was found in homovanillic acid level in the n. accumbens and tuberculum olfactorium. Specific binding of [3…
Serotonin metabolism and serotonergic receptors in Norway rats selected for low aggressiveness to man
Selection of Norway rats (24–27 generations) for low aggressiveness to man resulting in the loss of aggressive responding to handling markedly influences the brain serotonergic system. In “domesticated” Norway rats levels of serotonin in the midbrain and hypothalamus and 5-hydroxyindole acetic acid in the hypothalamus were higher than in non-selected aggressive rats. The activity of the key enzyme in serotonin biosynthesis, tryptophan hydroxylase…
Predatory aggression in the mink (Mustela vison)
5-Hydroxytrypotophan at a dose of 50 mg/kg intraperitoneally (i.p.) sharply increased neural serotonin (5-HT) levels in mink and considerably inhibited that animal's predatory attack on rats. Intraperitoneal injection of 5-HT (10 and 20 mg/kg) did not influence such rat-killing. Neural levels of 5-HT or 5-hydroxyindoleacetic acid (5-HIAA) and subsequent aggression by the predator did not change to any great degree after ingestion of a single meal…
Serotonin's influence on predatory behavior of highly aggressive cba and weakly aggressive DD strains of mice
The effects of serotonin were studied on locust-killing behavior of mice from low (DD) and high (CBA) predatory aggressive strains. 5-HTP injected intraperitoneally (50 and 100 mg/kg) or 5-HT administered into the lateral ventricle (10 μg) significantly reduced locust-killing behavior in highly aggressive CBA mice. Imipramine (20, 30, and 40 mg/kg) elicited a dose-dependent inhibitory effect on predatory behavior. Fluoxetine (10 and 20 mg/kg) alo…
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Serotonin's influence on predatory behavior of highly aggressive cba and weakly aggressive DD strains of mice
The effects of serotonin were studied on locust-killing behavior of mice from low (DD) and high (CBA) predatory aggressive strains. 5-HTP injected intraperitoneally (50 and 100 mg/kg) or 5-HT administered into the lateral ventricle (10 μg) significantly reduced locust-killing behavior in highly aggressive CBA mice. Imipramine (20, 30, and 40 mg/kg) elicited a dose-dependent inhibitory effect on predatory behavior. Fluoxetine (10 and 20 mg/kg) alo…
Predatory aggression in the mink (Mustela vison)
5-Hydroxytrypotophan at a dose of 50 mg/kg intraperitoneally (i.p.) sharply increased neural serotonin (5-HT) levels in mink and considerably inhibited that animal's predatory attack on rats. Intraperitoneal injection of 5-HT (10 and 20 mg/kg) did not influence such rat-killing. Neural levels of 5-HT or 5-hydroxyindoleacetic acid (5-HIAA) and subsequent aggression by the predator did not change to any great degree after ingestion of a single meal…
Serotonin metabolism and serotonergic receptors in Norway rats selected for low aggressiveness to man
Selection of Norway rats (24–27 generations) for low aggressiveness to man resulting in the loss of aggressive responding to handling markedly influences the brain serotonergic system. In “domesticated” Norway rats levels of serotonin in the midbrain and hypothalamus and 5-hydroxyindole acetic acid in the hypothalamus were higher than in non-selected aggressive rats. The activity of the key enzyme in serotonin biosynthesis, tryptophan hydroxylase…
Role of 5HT1A receptors in a variety of kinds of aggressive behavior in wild rats and counterparts selected for low defensiveness towards man
The 5HT1A receptor agonist ipsapirone (10 mg/kg) suppressed shock-induced aggression in wild and domesticated rats but did not affect predatory aggression in either group of animals. Ipsapirone decreased neophobia and inhibited defensive reactions by wild rats towards man in the glove test. [3H]8-OH-DPAT binding, which labels 5HT1A receptors, was significantly increased in the hypothalamus of domesticated rats in comparison with wild counterparts…
Selection for reduced aggressiveness towards man and dopaminergic activity in Norway rats
The brain dopaminergic system is involved in the process of long-term selection for reduced aggressive reaction towards man in Norway rats. The dopamine levels in the striatum as well as the nucleus accumbens with the tuberculum olfactorium were significantly lower in domesticated rats than in their wild counterparts. A substantial decrease was found in homovanillic acid level in the n. accumbens and tuberculum olfactorium. Specific binding of [3…
Defensive reactions of “wild-type” and “Domesticated” wild rats to approach and contact by a threat stimulus
Selective breeding of wild rats over many generations on the basis of low or high defensive threat and attack to human approach and contact has produced highly polarized “domesticated” and “wild-type” animals. Because the selection procedure selectively involves these two defense patterns, and these clearly differ in the two groups, it is of interest to determine if other, nonselected, defensive behaviors to threat stimuli also change. “Domestica…
Biology (6 works) · Medicine (6 works) · Endocrinology (5 works) · Internal Medicine (5 works) · Neuroendocrine regulation and behavior (5 works) · Receptor (5 works) · Chemistry (4 works) · Neurotransmitter Receptor Influence on Behavior (4 works) · Serotonin (4 works) · 5-HT receptor (3 works)