Internal validation of an improved system for forensic application

A 41-plex Y-STR panel

Bibliographic Data

ID13119810
AuthorsSiyu Chai (Zunyi Medical University, corresponding author), Min Li (0000-0002-1163-8961, Institute of Forensic Science), Ruiyang Tao (0000-0002-4618-1893, Institute of Forensic Science), Ruocheng Xia (Institute of Forensic Science), Qianqian Kong (0000-0002-6812-9535, Shanghai Key Laboratory of Forensic Medicine, Shanghai Forensic Service Platform, Academy of Forensic Sciences, Ministry of Justice , China, Shanghai , China), Qian-Qian Kong (Institute of Forensic Science), Yiling Qu (0000-0003-2746-2734, Soochow University), Liqin Chen (0000-0002-6513-8217, Inner Mongolia Medical University), Shiquan Liu (0000-0003-0141-1891, China University of Political Science and Law), Chengtao Li (0000-0001-6852-9144, Institute of Forensic Science), Pengyu Chen (0000-0003-4584-2036, Zunyi Medical University), Suhua Zhang (0000-0002-3984-9728, Shanghai Medical College of Fudan University)
Year2023
Volume8
Issue1
Pages70-78
Publication date2023-03-01
Peer ReviewedYes
Open AccessYes
TypeARTICLE
VenueForensic Sciences Research (JOURNAL)
Journal identifiersISSN: 2471-1411 • E-ISSN: 2096-1790
PublisherTaylor & Francis (PUBLISHER • GB)
DOI10.1093/fsr/owad012
PMID37415794
OpenAlexW4364374373
LanguageEN
Citations received1
References cited32

A novel multiplex comprising 41 Y-STR and 3 Y-InDel was developed for forensic application.The multiplex included rapidly mutating Y-STRs and low-medium mutating Y-STRs, which is compatible with many commonly used Y-STR kits.The multiplex is a powerful tool for distinguishing related males, familial searching, and constructing DNA databases

Amplicon · Biology · Computational biology · Concordance · Gene · Genotype · Genotyping · Indel · INDEL Mutation · Microsatellite · Multiplex · Multiplex polymerase chain reaction · Polymerase chain reaction · Population · Single-nucleotide polymorphism · STR analysis · STR multiplex system · Y chromosome · Y-STR · Forensic and Genetic Research · Genetic diversity and population structure · Medicine · Molecular Biology Techniques and Applications · Genetics

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