Genetic disenhancement and xenotransplantation
Diminishing pigs’ capacity to experience suffering through genetic engineering
Bibliographic Data
| ID | 21515399 |
|---|---|
| Authors | Daniel Rodger (0000-0002-2121-7167, London South Bank University, corresponding author), Daniel J Hurst (0000-0003-0592-2592, Department of Family Medicine, Rowan University School of Osteopathic Medicine, Stratford, New Jersey, USA), Chris Bobier (0000-0003-4194-4721, Saint Mary's University of Minnesota), Christopher A Bobier (Saint Mary's University of Minnesota, Winona, Minnesota, USA), Xavier Symons (0000-0002-9495-4395, Institute for Quantitative Social Science, Harvard University, Cambridge, Massachusetts, USA) |
| Year | 2024 |
| Volume | 50 |
| Issue | 11 |
| Pages | 729-733 |
| Publication date | 2024-11-01 |
| Peer Reviewed | Yes |
| Open Access | No |
| Type | ARTICLE |
| Venue | Journal of Medical Ethics (JOURNAL) |
| Journal identifiers | ISSN: 0306-6800 • E-ISSN: 1473-4257 |
| Publisher | BMJ (PUBLISHER • GB) |
| DOI | 10.1136/jme-2023-109594 |
| PMID | 38395623 |
| OpenAlex | W4392094539 |
| Language | EN |
| Citations received | 8 |
| References cited | 31 |
One objection to xenotransplantation is that it will require the large-scale breeding, raising and killing of genetically modified pigs. The pigs will need to be raised in designated pathogen-free facilities and undergo a range of medical tests before having their organs removed and being euthanised. As a result, they will have significantly shortened life expectancies, will experience pain and suffering and be subject to a degree of social and environmental deprivation. To minimise the impact of these factors, we propose the following option for consideration—ethically defensible xenotransplantation should entail the use of genetic disenhancement if it becomes possible to do so and if that pain and suffering cannot be eliminated by other means. Despite not being a morally ideal ‘solution’, it is morally better to prevent unavoidable pain until a viable non-animal alternative becomes available
Bioethics · Engineering ethics · Environmental ethics · Pain and suffering · Political science · Xenotransplantation · Engineering · Law · Medicine · Neuroethics, Human Enhancement, Biomedical Innovations · Philosophy · Pluripotent Stem Cells Research · Psychology · Xenotransplantation and immune response · Surgery · Transplantation
Ethically defensible executions? A reply to Daniel Rodger and coauthors
Defending genetic disenhancement in xenotransplantation
Prioritisation and non-sentientist harms
Allowing for open debate in medical ethics
Proceeding with care
This little piggy can’t leave the open market
Xenotransplantation
Bodyoids and Speculative Bioethics
| Unique citing works | 8 |
|---|---|
| Citations per year | 4 |
| Citation span | 2024 - 2026 (3) |
| Citation velocity | current |
| Highly cited | No |
| Citation types | Neutral: 8 |