An Integrative Theory of Prefrontal Cortex Function
Bibliographic Data
| ID | 23328121 |
|---|---|
| Authors | Earl K Miller (0000-0002-0582-6958, Massachusetts Institute of Technology), Jonathan D Cohen (0000-0003-2316-0763, Center for the Study of Brain, Mind, and Behavior and Department of Psychology, Princeton University, Princeton, New Jersey 08544) |
| Year | 2001 |
| Volume | 24 |
| Issue | 1 |
| Pages | 167-202 |
| Publication date | 2001-03-01 |
| Peer Reviewed | Yes |
| Open Access | No |
| Type | ARTICLE |
| Venue | Annual Review of Neuroscience (BOOK_SERIES) |
| Journal identifiers | ISSN: 0147-006X • E-ISSN: 1545-4126 |
| Publisher | Annual Reviews (PUBLISHER • US) |
| DOI | 10.1146/annurev.neuro.24.1.167 |
| PMID | 11283309 |
| OpenAlex | W2151137320 |
| Language | EN |
| Citations received | 593 |
| References cited | 183 |
The prefrontal cortex has long been suspected to play an important role in cognitive control, in the ability to orchestrate thought and action in accordance with internal goals. Its neural basis, however, has remained a mystery. Here, we propose that cognitive control stems from the active maintenance of patterns of activity in the prefrontal cortex that represent goals and the means to achieve them. They provide bias signals to other brain structures whose net effect is to guide the flow of activity along neural pathways that establish the proper mappings between inputs, internal states, and outputs needed to perform a given task. We review neurophysiological, neurobiological, neuroimaging, and computational studies that support this theory and discuss its implications as well as further issues to be addressed
Action (physics) · Cognition · Cognitive psychology · Cognitive science · Consumer neuroscience · Functional neuroimaging · Neuroimaging · Neurophysiology · Prefrontal cortex · Self-reference effect · Task (project management) · Memory and Neural Mechanisms · Neural and Behavioral Psychology Studies · Neural dynamics and brain function · Neuroscience · Psychology
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Insensitivity to future consequences following damage to human prefrontal cortex
Common regions of the human frontal lobe recruited by diverse cognitive demands
Specific impairments of planning
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A capacity theory of comprehension
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On the control of automatic processes
Working memory, short-term memory, and general fluid intelligence
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Neural networks and physical systems with emergent collective computational abilities.
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Half a century of research on the Stroop effect
Half a century of research on the Stroop effect
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Evolving conceptions of memory storage, selective attention, and their mutual constraints within the human information-processing system
| Unique citing works | 593 |
|---|---|
| Citations per year | 23,72 |
| Citation span | 2001 - 2026 (26) |
| Citation velocity | current |
| Highly cited | Yes |
| Citation types | Neutral: 526 |